Synthetic Methods for Conversion of Linear Peptides into Peptide Macrocycles
Synthetic Methods for Conversion of Linear Peptides into Peptide Macrocycles
批准号:
1942975
负责人:
金额:
$0.0万
依托单位:
依托单位国家:
英国
项目类别:
Studentship
财政年份:
2017
资助国家:
英国
项目状态:
已结题
起止时间:
2017 至 --
中文摘要
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英文摘要
This project describes the development of a method to turn native linear peptides into non-natural macrocyclic ligands. Based on reactions at site-specific peptide conjugates, a catalyst will enable linkage to tryptophan, tyrosine and histidine amino acids residues, resulting in the peptide macrocycles. These new macrocyclic molecules can be used to probe protein-protein interactions in disease-related systems.
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国内基金
海外基金
Computational Methods for Analyzing Toponome Data
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批准号:60601030
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项目类别:青年科学基金项目
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资助金额:17.0万元
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批准年份:2006
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负责人:Axel Mosig
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依托单位: