NEUROBIOLOGY OF MILD COGNITIVE IMPAIRMENT IN THE ELDERLY

《轻度认知的神经生物学》项目 《老年人的精神障碍》汇聚了许多基础科学家 以及来自芝加哥和其他大学的临床医生科学家。这个 该项目将设在拉什长老会-圣彼得堡。卢克医疗中心 在芝加哥。该计划项目由一个管理核心组成 具有临床/组织分布组件和统计数据 数据管理核心。此外，还进行了以下四项研究 项目完成计划：1)Tau异常和轻度 老年人的认知障碍(约翰·特罗亚诺夫斯基) 宾夕法尼亚州，项目负责人)；2)年龄相关神经病理学和 老年人的轻度认知障碍(丹尼斯·迪克森，阿尔伯特 爱因斯坦医学院，项目负责人)；3)胆碱能基础 前脑神经营养异常与轻度认知功能障碍 老年人(Elliott Mufson，项目负责人)；以及Synaptic 老年人的异常和轻度认知障碍(Steven DeKosky，匹兹堡大学，项目1Leader)。每个核心都将 支持所有这些研究项目。此外，这些项目将 从NIA资助的Rush获得临床数据和组织样本 ADC宗教秩序研究核心和神经病理学核心 所有项目。

The Program Project entitled "Neurobiology of Mild Cognitive Impairment in the Elderly" brings together a number of basic scientists and clinician scientists from Chicago and outside universities. The project will be based at Rush Presbyterian-St. Luke's Medical Center in Chicago. The Program Project consists of an Administrative Core with a Clinical/Tissue Distribution component and a Statistics and Data Management Core. In addition the following four research projects complete the program: 1) Tau abnormalities and Mild Cognitive Impairment in the Elderly (John Trojanowski, University of Pennsylvania, project leader); 2) Age-Related Neuropathology and Mild Cognitive Impairment in the Elderly (Dennis Dickson, Albert Einstein College of Medicine, project leader); 3) Cholinergic Basal Forebrain Neurotrophic Abnormalities and Mild Cognitive Impairment in the Elderly (Elliott Mufson, Project Leader); and Synaptic Abnormalities and Mild Cognitive Impairment in the Elderly (Steven DeKosky, University of Pittsburgh, project 1Leader). Each core will support all of these research projects. Moreover, these projects will receive clincial data and tissue samples from the NIA funded Rush ADC Religious Orders Study Core and the Neuropathology Core for all projects.