CORE--GENETIC EPIDEMIOLOGY AND BIOSTATISTICS

遗传流行病学和生物统计学核心结合了 鲍曼·格雷医学院的遗传分析与经验 在鲍曼·格雷和伯明翰阿拉巴马大学的生物统计学中， 为了方便实验数据的收集，数据管理， 统计和遗传数据分析。基因工程的目标 流行病学和生物统计学的核心是促进跨学科 在系统性红斑狼疮领域的研究，重点是测量的环境风险 因素、遗传风险因素及其交互作用(1) 针对特定基因量身定做的适当实验设计 假设，(2)促进有效的数据收集程序 每个项目站点用于数据传输，(3)开发标准化数据 传输过程以允许高效和有用的数据提取 分析，以及(4)提供最先进的纵向统计和 遗传数据分析。 遗传流行病学和生物统计学核心的长期目标是 利用收集的系统性红斑狼疮患者的遗传和流行病学数据 他们的家庭成员，以确定基因和环境风险 单独和共同导致SLE易感性的因素。

The Genetic Epidemiology and Biostatistics Core combines the expertise in genetic analysis of the Bowman Gray School of Medicine with the experience in biostatistics in Bowman Gray and the University of Alabama, Birmingham, to facilitate collection of experimental data, data management, statistical and genetic data analysis. The goals of the Genetic Epidemiology and Biostatistics Core are to promote interdisciplinary research in the area of SLE, with a focus on measured environmental risk factors, genetic risk factors and their interaction by (1) addressing appropriate experimental designs tailored to address specific genetic hypotheses, (2) facilitating an efficient data collection procedure at each project site for data transfer, (3) developing standardized data transfer procedures to allow efficient and useful data extraction for analysis, and (4) providing state-of-the-art longitudinal statistical and genetic data analysis. The long-term goals of the Genetic Epidemiology and Biostatistics Core are to utilize genetic and epidemiologic data collect on SLE patients and their family members in order to identify genes and environmental risk factors that singly and jointly contribute to the susceptibility for SLE.