Radiation Field Modeling/Computerized Treatment Planning

近年来，医学成像和定位技术的巨大进步给物理学和计算机技术带来了挑战，以扩展计算机化治疗规划和优化的能力。目前和最终的版本已经在Windows NT/2000平台上进行了临床使用验证。Windows NT版本现在是标准的临床治疗计划平台，Macintosh平台将停止使用。NT版本基于OpenGL图形引擎，可提供卓越的3D图像显示和操作。提出了一种新的基于实时体绘制的交互式图像融合算法。虽然目前这是用于CT和MRI图像，但任何图像集都可以融合。实施了RTOG格式的文件/图像导入和导出，以便与劳伦斯·利弗莫尔国家实验室进行通信。2001财政年度将实施DICOM-RT格式的导入和导出，以便与CIT一起与Telesynergy放射成像工作站项目进行通信。与LLNL的通信允许使用他们的游戏法蒙特卡罗剂量计算引擎进行临床研究项目。该引擎还将用于验证NIH-TPS的光子剂量计算方法。还计划将TPS用于立体定向放射外科/放射治疗(SRS/SRT)以及调强放射治疗(IMRT)。已经开发了一个用于近距离放射治疗的单独程序，该程序使用AAPM TG-43公式进行计算。对角度和径向剂量函数进行了修改，以允许血管内近距离放射治疗的治疗计划。我们正在洽谈CRADA，以进一步开发该系统，包括剂量优化和纳入实时体绘制技术。

The vast improvements of the medical imaging and localization technology over recent years has brought a challenge to physics and computer technology to extend the capabilities of computerized treatment planning and optimization. The current and final release has been validated for clinical use on Windows NT/2000 platforms. The Windows NT version is now the standard clinical treatment planning platform and the Macintosh platform will be discontinued. The NT version is based on the OpenGL graphics engine, which provides superior 3D image display and manipulation. A new interactive algorithm has been developed for image fusion using real-time volume rendering. Although this is currently used with CT and MRI images, any image set can be fused. File/image import and export in RTOG format has been implemented for communication with Lawerence Livermore National Laboratory. Import and export in DICOM-RT format will be implemented in FY-2001 for communication with the Telesynergy Radiological Imaging Workstation Project in conjunction with CIT. Communication with LLNL permits a clinical research project using their PEREGRINE Monte Carlo dose calculation engine. This engine will also be used to validate the photon dose calculation methodology of the NIH-TPS. Also planned is the use of the TPS for stereotactic radiosurgery/radiotherapy (SRS/SRT) as well as Intensity Modullated Radiotherapy (IMRT). A separate program for brachytherapy has been developed, which performs calculations using the AAPM TG-43 formalism. Modifications to the angular and radial dose functions have been made to permit treatment planning for intravascular brachytherapy. We are in the process of negoating a CRADA for further development of the system, including dose optimization and incorporating real-time volume rendering technology.