Perking up the Suzuki reaction with Co-Fe

铃木反应是生产新的碳-碳键的有力工具，并在工业上得到利用，例如用于治疗高血压的沙坦类药物的中间体合成和农用化学杀菌剂的生产。尽管铃木反应具有很高的实用性，但它需要使用钯基催化剂。钯价格昂贵，毒性较大，提取过程对环境影响较大。在这项研究中，我们将基于更便宜、更良性和可持续的金属铁和钴生产新型均相催化剂。我们将特别关注能够形成C(sp2)-C（sp2）键的催化剂的开发，因为事实证明，用第一排过渡金属基催化剂来实现这一目标尤其具有挑战性，但潜在的工业终端用户对此特别感兴趣。

The Suzuki reaction is a powerful tool for the production of new carbon-carbon bonds and is exploited industrially, for instance in the synthesis of intermediates for the sartan class of drugs for treating high blood pressure and in the production of agrochemical fungicides. Despite its high utility, the Suzuki reaction suffers from the need to use palladium-based catalysts. Palladium is expensive, relatively toxic and its extraction environmentally impacting. In this research, we will produce new classes of homogeneous catalysts based on the far cheaper, more benign and sustainable metal iron and cobalt. In particular we will focus on the development of catalysts that are capable of C(sp2)-C(sp2) bond-formation as these have proven to be particularly challenging to achieve with first row transition metal-based catalysts, yet are of particular interest to potential industrial end-users.