Elucidating the mechanism and function of cell disassembly during apoptosis

阐明细胞凋亡过程中细胞解体的机制和功能

• 批准号: nhmrc : GNT1125033
• 负责人: Dr Ivan Poon
• 金额: $ 42.5万
• 依托单位: La Trobe University
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/elucidating-mechanism-function-disassembly-apoptosis/1347452
• 关键词: Elucidating; mechanism; function; cell; disassembly

In humans, billions of cells will die daily in various organs as part of normal turnover and disease progression. During cell death, dying cells can disassembly in to smaller fragments, a process that could facilitate their removal, as well as mediate communication with other healthy cells. I aim to understand the machinery that control how dying cells can disassemble into smaller pieces and their function in influenza A infection.

在人类中，每天有数十亿个细胞在各种器官中死亡，作为正常周转和疾病进展的一部分。在细胞死亡过程中，垂死的细胞可以分解成更小的碎片，这一过程可以促进它们的去除，并介导与其他健康细胞的交流。我的目标是了解控制垂死细胞如何分解成更小碎片的机制及其在甲型流感感染中的作用。