Molecular mechanisms of apoptotic cell clearance

凋亡细胞清除的分子机制

• 批准号: nhmrc : 1013584
• 负责人: Dr Ivan Poon
• 金额: $ 22.32万
• 依托单位: La Trobe University
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/molecular-mechanisms-apoptotic-cell-clearance/109730
• 关键词: Molecular; mechanisms; apoptotic; cell; clearance

Billions of cells are destined to die everyday as a part of normal development and tissue homeostasis. A failure to clear dying cells rapidly and efficiently can lead to chronic inflammation, autoimmunity and developmental defects. This research project aims to investigate how the immune system detects the presence of dying cells and removes them efficiently.

作为正常发育和组织稳态的一部分，每天有数十亿细胞注定要死亡。不能快速有效地清除垂死细胞会导致慢性炎症、自身免疫和发育缺陷。该研究项目旨在研究免疫系统如何检测垂死细胞的存在并有效地将其清除。