Nutritional Biochemistry and Epidemiology of Cancer

描述（由申请人提供）：这是唯一的培训计划，最初于1997年资助专门关注营养和癌症的第一次更新。 虽然它享有相当大的校内支持，并被认为是癌症研究的主要前景，相对较少的NCI外部资金集中在营养和癌症领域。 营养研究非常引人注目，但也涉及极其复杂的研究设计，充满了测量误差，潜在的偏见，并且由于饮食成分和模式之间的相互关系而变得复杂。 需要强有力的培训计划，以招募最好的科学家进入这一领域，并提供支持，以发展所需的能力，以推进科学和将新技术纳入该领域。 我们已经设计了一个培训计划，以满足我们的研究社区的需要，训练有素，方法学上先进的科学家愿意把他们的研究事业集中在营养和癌症，通过招聘优秀的科学家到外地和交叉培训他们在营养生物化学，营养流行病学和癌症研究方法。 为了准备研究员在营养和癌症研究的职业生涯，该计划有四个具体的目标或培训目标。 在多学科培训咨询委员会和导师小组的指导下，研究员将学习与致癌营养研究有关的基本生物化学和流行病学，掌握这一领域的核心研究方法;在一个特定的主题领域进行研究，这将进一步我们的饮食和癌症的知识和专业发展，使他们能够成功的道德动机，在这一领域走向学术生涯的富有成效的研究人员。 为此，我们每年申请两个博士后和六个博士前实习生职位。

DESCRIPTION (provided by applicant): This is the first renewal of the only training program focusing exclusively on nutrition and cancer that was originally funded in 1997. Although it enjoys considerable intramural support, and is recognized as a major promising of cancer research, relatively little of NCI external funding is focused on the area of nutrition and cancer. Nutritional research is very compelling but also involves study designs that are extremely complex, fraught with measurement error, potential biases and is complicated by interrelations among dietary components and patterns. Strong training programs are needed to recruit the best scientists into this area and to provide support in developing the competencies needed to advance the science and incorporate new technologies into the field. We have designed a training program to meet the need of our research community for well-trained and methodologically sophisticated scientists willing to focus their research careers on nutrition and cancer through recruitment of excellent scientists to the field and cross training them in nutritional biochemistry, nutritional epidemiology, and cancer research methods. To prepare fellows for careers in nutritional and cancer research, the program has four specific aims or training objectives. Under the direction of a multidisciplinary Training Advisory Committee and preceptor team, fellows will learn the fundamental biochemistry and epidemiology relevant to nutritional research on carcinogenesis, become competent in research methods central to this field; conduct research in a specific topic area that will further our knowledge of diet and cancer and develop professionally so they can succeed as ethically motivated, productive researchers heading towards academic careers in this field. We are requesting two postdoctoral and six predoctoral trainee positions each year for this purpose.