Elucidating the role of transthalamic pathways in cortical processing

阐明经丘脑通路在皮质处理中的作用

• 批准号: nhmrc : 2003646
• 金额: $ 79.27万
• 依托单位国家: 澳大利亚
• 项目类别: Ideas Grants
• 财政年份: 2022
• 资助国家: 澳大利亚
• 起止时间: 2022-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/elucidating-role-transthalamic-cortical-processing/1780182
• 关键词: Elucidating; role; transthalamic; pathways; cortical

Your brain senses the world and produces a suitable motor response by processing information between brain regions, such as primary sensory cortex to secondary cortex. Surprisingly, cortical pathways have a parallel route through the thalamus (transthalamic pathways) but their function is entirely unknown. We will use novel genetic and viral tools to shut down neural pathways while mice make decisions, thus identifying new circuits in our understanding of disorders with cognitive deficits.

你的大脑感知世界，并通过处理大脑区域之间的信息产生适当的运动反应，例如初级感觉皮层到次级皮层。令人惊讶的是，皮质通路有一条平行的途径通过丘脑（经丘脑通路），但它们的功能完全未知。我们将使用新的遗传和病毒工具来关闭神经通路，而小鼠做出决定，从而在我们对认知缺陷障碍的理解中确定新的回路。