RETARGETING MID LIFE AND OLDER SMOKERS

描述(申请人摘要)：50岁以上的吸烟者超过1300万 在美国，他们往往是重度、长期吸烟者，他们更 可能因吸烟而引起或加重慢性病的。正在停止 吸烟可以降低致残性疾病的发病率和死亡率 在整个生命周期内的状况。因此，吸烟和吸烟的含义 停止为老年人维持健康和独立生活 种群数量可观。关于有效治疗的数据很少。 在这个不断增长的人口中吸烟。辅助自助干预似乎 特别适合于这一群体，他们可能受到地理或 获得吸烟干预服务的能力方面的健康状况。 目前和之前的试验的初步结果表明 积极主动的远程销售，结合自助手册和访问 反应性戒烟可以提高戒烟率，特别是在那些使用 同时进行戒烟药物治疗。其他试验的结果 表明要实现吸烟，经常需要多次戒烟 节欲和远程电话销售可能会促进循环利用(即，在 尝试失败)。拟议的研究将扩大目前试验的范围 检查戒烟失败后回收50岁以上吸烟者的有效性 过去两年的尝试(从目前的审判和 辅以社区新兵)。将对两组进行比较：1)最小 干预控制-自助手册和访问反应性退出热线 (吸烟者拨打戒烟热线寻求帮助)；以及2)主动-手册和 Quitline和主动远程呼叫(向参与者发出呼叫) 支持FDA批准的药物疗法的戒烟和支持使用 用于戒烟(尼古丁替代品、安非他酮和其他，如果它们是 在研究期间获得批准。受试者将在6岁、12岁和18岁时接受跟踪 评估吸烟状况、健康后果和戒烟使用情况的月数 资源(手动、停机、主动远程咨询、药物治疗)

DESCRIPTION (Applicant's abstract): There are over 13 million smokers ages 50+ in the United States, who tend to be heavy, long-term smokers who are more likely to have chronic diseases caused or exacerbated by smoking. Stopping smoking can reduce morbidity and mortality from disabling diseases and conditions across the lifespan. Thus, the implications of smoking and smoking cessation for maintenance of health and independent living for older populations are considerable. Little data are available on effective treatments for smoking in this growing population. Assisted self-help interventions seem particularly appropriate to this group, who may be limited geographically or by health status in their ability to access smoking intervention services. Preliminary results from the current and preceding trials suggest that proactive telecounseling, in combination with a self-help manual and access to a reactive quitline, enhances quit rates, particularly among those using concurrent pharmacotherapy for smoking cessation. Results of other trials indicate that multiple quit attempts are often necessary to achieve smoking abstinence, and telecounseling may enhance recycling (i.e., re-quitting after a failed attempt). The proposed study will extend the scope of the current trial to examine the effectiveness of recycling smokers ages 50+ with a failed quit attempt in the past two years (recruited from the current trial and supplemented with community recruits). Two groups will be compared: 1) Minimal Intervention Control - self-help manual and access to a reactive quitline (smokers call in to the quitline for assistance); and 2) Proactive - manual and quitline along with proactive telecounseling calls (calls out to participants) to supporting re-quitting and supporting use of FDA approved pharmacotherapies for smoking cessation (nicotine replacement, bupropion, and others if they are approved during the period of study. Subjects will be followed at 6, 12, and 18 months for assessment of smoking status, health outcomes, and use of cessation resources (manual, quitline, proactive telecounseling, pharmacotherapy)