NICOTINE DEPENDENCE AMONG US YOUTHS

描述(改编自申请人的摘要)：本建议书请求 支持研究流行病学的四年(411/00-3131104)，相关 和尼古丁依赖的危险因素在全国纵向样本中 18至24岁的美国青少年，全国青少年纵向研究 健康(增加健康)(Resnick等人，1997；Ury，1998)。请拨出资金以 包括关于尼古丁依赖的额外采访数据和两个 此前未在下一波数据中确定的假设风险因素 收集工作将于2000年实施(2000年第三波调查)。 建议的研究有三个具体目的：(1)描述流行病学 尼古丁依赖的自然病史和吸烟的其他方面 行为，特别是终生吸烟、每日吸烟和吸烟量， 在美国年轻人中。(2)找出心理和社会因素 关联和预测吸烟开始、每日吸烟、吸烟量和 尼古丁依赖(危险因素)和降低发病风险的因素， 每日吸烟、吸烟量和尼古丁依赖(保护因素)。 (3)确定性别和种族在以下方面的共同点和差异 目标1号和2号。 为了实现这些目标，将在第三波 增加对20,000多名18-24岁青年的健康数据收集，首次采访 年龄在12-18岁之间。该样本构成了具有全国代表性的 以前是7-12年级的学生，包括一对双胞胎的遗传信息样本， 完全兄弟姐妹、同父异母兄弟姐妹和不相关的配对。 随着新问题的增加，关于流行性感冒流行病学的独特数据 尼古丁依赖将在具有全国代表性的 我们年轻人，拥有丰富的纵向信息来源。这些数据将是 可供其他调查人员使用，因为Add Health数据是以公开形式发布的 使用数据集。 拟议的研究将产生对流行病学的独特理解， 吸烟和尼古丁依赖的自然病史、相关因素和病因 在年轻人中

DESCRIPTION (Adapted from the Applicant's Abstract): This proposal requests four years of support (411/00-3131104) to study the epidemiology, correlates and risk factors for nicotine dependence in a national longitudinal sample of US youths 18 to 24 years old, the National Longitudinal Study of Adolescent Health (Add Health) (Resnick et al., 1997; Udry, 1998). Funds are requested to cover the inclusion of additional interview data on nicotine dependence and two hypothesized risk factors not previously ascertained in the next wave of data collection to be implemented in the year 2000 (Wave III Survey 2000). The proposed research has three specific aims: (1) To describe the epidemiology and natural history of nicotine dependence and other aspects of smoking behavior, in particular lifetime smoking, daily smoking and quantity smoked, among US youths. (2) To identify psychological and social factors that correlate and predict smoking onset, daily smoking, quantity smoked and nicotine dependence (risk factors) and factors that reduce the risk of onset, daily smoking, quantity smoked and nicotine dependence (protective factors). (3) To identify gender and ethnic commonalties and differences with respect to Aims #1 and #2. To achieve these aims, additional data will be obtained in the third wave of Add Health data collection on over 20,000 youth aged 18-24, first interviewed at ages 12-18. The sample constitutes a national representative sample of former 7th-12th graders, and includes a genetically informative sample of twin, full sibling, half sibling and unrelated pairs. With the addition of the new questions, unique data on the epidemiology of nicotine dependence will be available for a nationally representative sample of US youths, with a rich source of longitudinal information. These data will be available to other investigators since Add Health data are released as a public use data set. The proposed study will generate a unique understanding of the epidemiology, natural history, correlates and etiology of smoking and nicotine dependence among young people