Drug Reduction Intervention for Needle Exchange Clients

描述：(申请人摘要) 注射吸毒者面临各种问题的风险，如艾滋病毒 感染、乙肝和丙型肝炎、心内膜炎、创伤、法律和工作困难 和家庭功能障碍。这项研究的目的是探索 为有效减少针具交换计划使用者的药物使用，其 参加这类服务可能标志着降低风险和 想摆脱吸毒的欲望。在过去的二十年里，短暂的干预 事实证明，它在减少各种环境中的药物滥用方面很有希望。 药物滥用治疗的最新进展强调了 利用基于动机的方法。然而，很少有研究考察 对吸毒者进行简短的基于动机的干预的可能性 参加针头交换计划可能会改善药物使用结果。 通过增加助推器会议来加强短暂干预可能会进一步 增强效能。 这一治疗结果研究计划机构的长期目标 是为成年药物滥用者提供有效的简短干预。这个 这项提案的具体目标是调查一项 激励性访谈有助于减少药物使用 在参加针头交换计划的注射吸毒者中， 注意安慰剂对照(2组设计中的AQ条件。患者会 在基线干预后1个月和6个月进行随访， 经尿检和家人或朋友的报告证实的自我报告。 主要结果变量包括吸毒总天数和 接受治疗的天数。假设接受MI的群体将表现出较低的 吸毒天数和药物滥用治疗天数 2)MI和结果变量之间的关系将随着 功能的变化取决于患者的准备程度。 这项研究将通过评估MI的使用来扩展先前的研究 针头交换参与者的个人。有效的发展 针对与初级保健联系不佳的人群的干预措施， 疾病负担和高艾滋病毒传播风险应该会降低慢性病 减少药物使用，增加药物治疗天数。

DESCRIPTION: (Applicant's Abstract) Injection drug users are at risk for a variety of problems such as HIV infection, hepatitis B and C, endocarditis, trauma, legal and work difficulties and family dysfunction. The objective of this research is to investigate ways to effectively reduce drug use among needle exchange program users, whose attendance at such services may signal the beginnings of risk reduction and a desire to escape drug use. In the past two decades brief interventions have proven to be promising in reducing substance abuse in a variety of settings. Recent developments in treatments for substance abuse underscore the primacy of utilizing motivation-based approaches. However, few studies have examined the likelihood that using a brief motivation based intervention with drug users enrolled in needle exchange programs may improve drug use outcomes. Intensifying brief intervention by adding a booster session might further enhance efficacy. The long-term objective of this programmatic body of treatment outcome research is to provide effective brief interventions for adult substance abusers. The specific aims of this proposal are to investigate the extent to which a Motivational Interview with a booster session is effective in reducing drug use among injection drug users enrolled in needle exchange programs as compared to an Attention Placebo Control (AQ condition in a 2-group design. Patients will be followed at 1-and 6 months after the baseline intervention, with self-reports confirmed by urine screens and reports of family or friends. Primary outcome variables include total number of drug use days and number of days in treatment. It is hypothesized that groups receiving MI will show lower levels of drug using days and more days of substance abuse treatment and that 2) the relationship between MI and the outcome variables will vary as a function of the patient's degree of readiness to change. This study will extend previous research by evaluating the use of MI with individuals who are needle exchange participants. The development of effective interventions for a population with poor linkage to primary care, an enormous burden of illness, and high HIV transmission risk should reduce the chronicity of drug use and enhance days in drug treatment.