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CORE--ANIMAL MODELS

CORE--ANIMAL MODELS
核心--动物模型
批准号：
6564256
负责人：
YVETTE FRANCE TACHE
金额：
$14.67万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2001
资助国家：
美国
项目状态：
已结题
起止时间：
2001-12-01 至 2002-11-30
来源：
https://reporter.nih.gov/project-details/6564256
关键词：
biological models biomedical facility blood flow measurement disease /disorder model electrophysiology gastrointestinal disorder gastrointestinal function laboratory mouse laboratory rat model design /development neuroregulation

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DESCRIPTION (Adapted from the application) The overall objectives of the core are to provide facilities and expertise to researchers for in vivo characterization of normal and pathophysiological mechanisms of hormonal and neural regulation of GI function and brain gut interactions. They provide the investigators with 1. In vivo experimental models to assess gastric, pancreatic, and intestinal function in rats, mice, and other species; 2. Specialized facilities and equipment for measuring GI secretory, motor, and nerve functions; 3. Methods for in vivo administration of peptides, neurotransmitters, and drugs, sampling blood and body fluids, and removing tissues; 4. Methods to assess afferent and efferent arms of the pathways in brain-gut interactions; and 5. Expertise in protocol design and data interpretation for in vivo studies.
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Mechanisms and therapeutic interventions of postoperative gastric ileus
Comprehensive Structural and Functional Mapping of Mammalian Colonic Nervous System
Comprehensive Structural and Functional Mapping of Mammalian Colonic Nervous System
Mechanisms of Postoperative Ileus
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