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COMPUTATIONAL METHODS IN GENETIC EPIDEMIOLOGY

COMPUTATIONAL METHODS IN GENETIC EPIDEMIOLOGY
遗传流行病学的计算方法
批准号:
6498753
负责人:
Duncan C. Thomas
金额:
$49.31万
依托单位国家:
美国
项目类别:
财政年份:
2000
资助国家:
美国
项目状态:
已结题
起止时间:
2000-02-01 至 2004-01-31

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英文摘要
In this grant, we propose to focus further work on computational problems in gene mapping studies, with particular emphasis on finding genes for complex traits combining linkage and linkage disequilibrium information. Combining research forces at both the University of Southern California (USC) and the Fred Hutchinson Cancer Research Center (FHCRC), we propose to explore the following approaches for joint linkage and linkage disequilibrium analysis: Maximum likelihood methods using both empirical models for disequilibrium and population genetics models for isolated and admixed populations. Efficient Estimating Equations (EEE) methods for semi-parametric analysis MCMC methods for larger pedigrees than are currently feasible.
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Exogenous and Genetic Determinants of the Internal Environment
  • 批准号:
    9072859
  • 项目类别:
  • 资助金额:
    $26.88万
  • 财政年份:
    2016
  • 负责人:
    Duncan C. Thomas
  • 依托单位:
Statistical Methods for Epigenetic Mediation of Exposure-response Relations
  • 批准号:
    8600681
  • 项目类别:
  • 资助金额:
    $16.26万
  • 财政年份:
    2012
  • 负责人:
    Duncan C. Thomas
  • 依托单位:
Statistical Methods for Epigenetic Mediation of Exposure-response Relations
  • 批准号:
    8219246
  • 项目类别:
  • 资助金额:
    $16.35万
  • 财政年份:
    2012
  • 负责人:
    Duncan C. Thomas
  • 依托单位:
Statistical Methods for Epigenetic Mediation of Exposure-response Relations
  • 批准号:
    8416895
  • 项目类别:
  • 资助金额:
    $16.07万
  • 财政年份:
    2012
  • 负责人:
    Duncan C. Thomas
  • 依托单位:
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