Physician Training Program in Neonatal Biology

描述（由申请人提供）：基于在培养医师科学家方面的卓越记录，本申请旨在通过增强研究者的优势和扩展研究者的能力来改进爱荷华大学现有的新生儿博士后培养计划。调查人员的目标是提供三个医学博士或医学博士/博士。在医学研究方面接受过2到3年严格的、高水平的、最先进的培训。研究人员的受训者将在强调科学卓越和团队协作的培养环境中获得必要的知识、技能和工作习惯。该项目的教师导师包括高级和中级科学家，他们作为医学研究人员和导师已经建立了成功的职业生涯。教职员工包括来自基础科学系（生物化学、解剖与细胞生物学、生理学和生物物理学）和临床医学系（儿科、内科、妇产科和耳鼻喉科）的一系列研究人员。培训生可利用的机构资源非常丰富。学员的选拔是竞争性的，基于他们成为独立的内科科学家的潜力，能够在研究和临床医学中担任领导角色。在选定教师导师和研究领域后，学员将在导师教师的五个研究领域之一进行基于假设的研究：发育生理学、发育生物学、基因治疗、分子遗传学和临床试验/流行病学。由于教师之间的重叠和合作研究兴趣，学员将有很多机会与不同范围的教师互动。每个受训者的研究项目将在受训者导师、项目主管和新生儿科导师的指导下，根据个人情况制定。除了参与实际的实验室经验外，学员还将通过参加研究研讨会、讲座和实验室会议，通过撰写研究提案、手稿和拨款，以及参加研究会议，直接了解高质量科学研究的本质。其他重要的因素是由新生儿科教师提供的小组支持和指导，并由拟议的项目和内部咨询委员会提供意见和监督。计划的有效性将以系统的方式进行前瞻性评估。在美国国立卫生研究院的支持下，研究人员将能够大大提高他们为新生儿医学博士后医师培训生提供的研究培训经验。

DESCRIPTION (provided by applicant): Building on the record of excellence in training physician-scientists, the present application seeks to improve upon the existing neonatology postdoctoral training program at the University of Iowa by enhancing the investigators' strengths and expanding the investigators' capabilities. The investigators' objective is to provide three M.D. or M.D./Ph.D. trainees with 2 to 3 years of rigorous, high caliber, state-of-the-art training in medical research. The acquisition of the requisite knowledge, skills, and work habits by the investigators' trainees will take place in a nurturing environment emphasizing scientific excellence and collaborative teamwork. The program's faculty preceptors include senior and mid-level scientists who have established successful careers as medical researchers and mentors. The faculty includes a spectrum of researchers from the departments of basic science (Biochemistry, Anatomy & Cell Biology, Physiology and Biophysics) and from clinical medicine (Pediatrics, Internal Medicine, Obstetrics and Gynecology, and Otolaryngology). Institutional resources available to trainees are outstanding. The selection of trainees is competitively based on their potential for becoming independent physician-scientists capable of assuming leadership roles in research and clinical medicine. After selecting a faculty preceptor and an area of research, trainees will pursue hypothesis-based research in one of the five research areas of the preceptor faculty's strengths: developmental physiology, developmental biology, gene therapy, molecular genetics, and clinical trials/epidemiology. Because of the overlapping and collaborative research interests among the faculty, trainees will have multiple opportunities to interact with a diverse spectrum of faculty. Each trainee's research program will be developed on an individual basis with input and guidance from the trainee's preceptor, the Program Directors, and the Neonatology preceptor faculty. In addition to engaging in hands-on laboratory experiences, trainees will learn directly about the nature of high quality scientific research by attending research seminars, lectures, and laboratory meetings, by writing research proposals, manuscripts, and grants, and by participating in research conferences. Other important elements are group support and mentoring by the neonatology faculty with input from and oversight by the proposed Program and Internal Advisory Committees. Proposed program's effectiveness will be prospectively evaluated in a systematic fashion. With NIH support beyond that which the investigators currently enjoy, the investigators will be able to significantly enhance the research training experiences they offer their postdoctoral physician trainees in neonatal medicine.