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Yale Cancer Center Advanced Training Program for Physician-Scientists (YCC-ATPP)

耶鲁大学癌症中心医师科学家高级培训计划 (YCC-ATPP)

基本信息

批准号：
10673642
负责人：
Lieping Chen
金额：
$ 33.03万
依托单位：
YALE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-08-01 至 2024-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10673642
关键词：
Yale Cancer Center physician-scientist training program

项目摘要

PROJECT SUMMARY/ABSTRACT This resubmission titled “Yale Cancer Center Advanced Training Program for Physician-scientists (YCC-ATPP)” requests five years of support for an intensive hematology and medical oncology (Heme/MedOnc) fellowship research training program at the Yale School of Medicine (YSM)/Yale Cancer Center (YCC). Our record of training Heme/MedOnc fellows is strong. Our trainees have gone on to major positions of leadership and success in academic and clinical hematology and oncology settings. Since 1987, 151 fellows have completed the Heme/MedOnc Fellowship Program (originally as separate disciplines; now as a joint program since 2012), and 46 of the 72 graduates who completed the program within the last 10 years work in academic positions, many with independent funding. Bolstered by the recent investment in our cancer center by Yale University and Yale-New Haven Hospital, including increased institutional commitment and faculty recruitment in recent years (many with peer-reviewed funding), we believe the structure and support provided by this T32 will allow trainees to achieve even greater success and will further increase the numbers of accomplished independent physician-scientist leaders completing our program. This T32 will build on a foundation of excellence established during clinical training in our Heme/MedOnc Fellowship Program, from which fellows will be able to apply to this program. As such, the prospective trainees will have already received an MD or MD/PhD degree, completed internal medicine residency, and 2 years of clinical fellowship training in Heme/MedOnc. This T32 program will select the most highly qualified and diverse candidates from this group who wish to pursue a career in cancer research and numerous procedures have been put in place to ensure the recruitment, quality mentorship, and retention of under-represented minority fellows. This advanced training program will provide outstanding mentored basic, translational, clinical, and outcome-based cancer research experiences from senior and expert junior faculty in a highly collegial, collaborative, and integrative institutional environment. This program is designed to provide essential financial support and ensure precious protected time is given to our fellows for research, allowing them to establish themselves early on as physician-scientists, and paving the way towards a successful academic career. Along these lines, the program includes career development planning and mentorship committees including scientists and physicians with knowledge and experience in the trainee’s research field to provide guidance throughout the length of the program. At the conclusion of their training, it is our goal that individuals supported by this T32 will have developed the skills necessary to function independently, including the ability to design, initiate, and complete research projects, and to effectively write grants and manuscripts. The T32 will firmly position Heme/MedOnc fellows as independent clinical, translational, or basic cancer researcher leaders of tomorrow.

项目总结/摘要这份重新提交的题为“耶鲁大学癌症中心高级培训计划的医生，科学家（YCC-ATPP）”要求为强化血液学和内科肿瘤学提供五年的支持 (Heme/MedOnc）耶鲁大学医学院（YSM）/耶鲁大学癌症研究培训项目中心（YCC）。我们培训Heme/MedOnc研究员的记录是强大的。我们的学员已经升到少校在学术和临床血液学和肿瘤学环境中的领导地位和成功。自1987年以来， 151名研究员完成了血红素/MedOnc奖学金计划（最初作为单独的学科;现在作为自2012年以来的联合计划），以及在过去10年内完成该计划的72名毕业生中的46名在学术职位上工作，许多人有独立的资金。在最近对癌症的投资支持下中心由耶鲁大学和耶鲁纽黑文医院，包括增加机构的承诺，教师招聘近年来（许多同行评审的资金），我们相信结构和支持 T32所提供的技术将使受训者取得更大的成功，并将进一步增加完成我们项目的有成就的独立医生-科学家领导者。这T32将建立在卓越的基础上建立在临床培训期间，在我们的 Heme/MedOnc奖学金计划，研究员可以申请该计划。因此，未来的学员将已经获得医学博士或医学博士/博士学位，完成内科学住院医师，并在Heme/MedOnc接受2年临床研究员培训。这个T32计划将选择最多的来自这一群体的高素质和多样化的候选人，他们希望从事癌症研究，已经制定了许多程序，以确保招聘、高质量的指导和留住少数族裔研究员人数不足。这种先进的培训计划将提供优秀的指导基本，翻译，临床和基于结果的癌症研究经验，从高级和专家初级教师在一个高度合议，协作和一体化的机构环境。该计划旨在提供必要的财政支持，并确保宝贵的保护时间给我们的研究员进行研究，他们建立自己的早期作为物理学家，科学家，并铺平道路，走向成功的学术生涯。沿着这些路线，该计划包括职业发展规划和指导委员会，包括在受训者研究领域具有知识和经验的科学家和医生，在整个项目期间提供指导。在训练结束后，我们的目标是，由该T32支持的个人将发展独立工作所需的技能，包括设计，启动和完成研究项目的能力，并有效地撰写赠款和手稿。 T32将坚定地将Heme/MedOnc研究员定位为独立的临床，转化或基础癌症未来的研究领导者

项目成果

期刊论文数量（4）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Intracranial Complications From Immune Checkpoint Therapy in a Patient With NSCLC and Multiple Sclerosis: Case Report.

DOI：
10.1016/j.jtocrr.2021.100183
发表时间：
2021-06
期刊：
JTO clinical and research reports
影响因子：
0
作者：
Lu BY;Isitan C;Mahajan A;Chiang V;Huttner A;Mitzner JR;Wesley SF;Goldberg SB
通讯作者：
Goldberg SB

Key Factors in Clinical Protocols for Adoptive Cell Therapy in Melanoma.

黑色素瘤过继细胞治疗临床方案的关键因素。