Career Acceleration Studentship in Organic Chemistry - The Development of Seamless Photochemical, Electrochemical and Thermochemical Daisy Chain Seque

有机化学职业加速助学金 - 无缝光化学、电化学和热化学菊花链序列的开发

• 批准号: 2102189
• 金额: --
• 依托单位: University of Southampton
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2102189
• 关键词: Career; Acceleration; Studentship; Organic; Chemistry

The project is linked to the EPRSC Programme Grant EP/P013341/1 in which we are seeking to develop clean photochemical, thermochemical and electrochemical reactions in flow for the production of industrially relevant fine chemicals. Our approach will begin with a period of familiarisation, where William will seeking to apply some of our recently developed flow photochemical reactions in target oriented synthesis. Phase 2 will seek to extend these protocols to an array of related systems leading to new routes for 3D scaffold synthesis with a minimal waste stream. Phase 3 will seek to add further complexity by using the output of a photochemical reaction as the direct feedstock for subsequent thermochemical and/or electrochemical steps. Such 'daisy-chain' processes impart novelty and complexity, with the promise of achieving close to 100% efficiency in atom economy in line with the ideals set out in the Dial-a-Molecule road map.

该项目与EPRSC计划赠款EP/P013341/1有关，我们正在寻求开发清洁的光化学，热化学和电化学反应，用于生产工业相关的精细化学品。我们的方法将开始与一段时间的熟悉，威廉将寻求应用我们最近开发的一些流动光化学反应在目标导向合成。第二阶段将寻求将这些协议扩展到一系列相关系统，从而以最小的废物流为3D支架合成提供新的途径。阶段3将寻求通过使用光化学反应的输出作为后续热化学和/或电化学步骤的直接原料来增加进一步的复杂性。这种“菊花链”工艺具有新奇和复杂性，有望实现接近100%的原子经济效率，符合Dial-a-Molecule路线图中提出的理想。