New Fluorinated MRI Probes for Cell Imaging
New Fluorinated MRI Probes for Cell Imaging
批准号:
6549921
负责人:
MANSSUR YALPANI
金额:
$11.75万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2002
资助国家:
美国
项目状态:
已结题
起止时间:
2002-09-30 至 2003-08-31
中文摘要
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英文摘要
DESCRIPTION (provided by applicant):New bio compatible probes are proposed for magnetic resonance imaging (MRI). 19F based probes will be prepared that are more suitable than existing products for rapid and sensitive oxygen mapping using 19F MRI. These probes will be employed to assess in a model system the viability, metabolic rate and oxygen consumption rates of rat INS-1 cells as surrogates of human is lets for potential applications in diabetes therapy. Preliminary data from pilot studies indicate that these new probes are promising and constitute a viable approach for improved cell viability control.
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批准号:6788073
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项目类别:
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资助金额:$11.63万
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财政年份:1996
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依托单位: