CORE--SHARED SCIENTIFIC RESOURCES

核心——共享科学资源

• 批准号: 6655142
• 负责人: Robert James Malcolm
• 金额: $ 24.29万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-01 至 2002-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6655142
• 关键词: alcoholism /alcohol abuse; biomedical facility; clinical research; data management; human subject; patient /disease registry; statistics /biometry

The Shared Scientific Resource Core was established in the Alcohol Research Center at the Medical University of South Carolina to facilitate the execution of alcohol treatment research, to improve research efficiency, to maximize resource utilization, and to provide quality control through standardization and centralization of services. The Core services provided were tailored to those most likely to be utilized by several projects as well as those most amenable to centralization. The progress made in addressing the original specific aims were outstanding. Individuals were hired and trained, critical systems were put into place, and services organization were refined over the course of the first few years. The resulting systems function smoothly, the Core services are utilized by many alcohol researchers funded both inside and outside of the Center grant, and demand for services continues to grow. By encouraging the various projects to work together, communication has been enhanced, a cohesive working unit has been established, database management has been efficient, and productivity has been increased. This renewal application proposes to continue three of the original specific aims and to add one new aim. The continuing Specific Aims are: 1) to continue to provide centralized subjective recruitment and screening; 2) to continue to provide centralized pharmacy, medical, and laboratory services; and 3) to continue to provide statistical and database management services. The new aim, Specific Aim 4, is to develop and provide centralized research assistant training. This latter aim represents a natural extension of our centralized functions and is expected to result in more uniformity across studies and enhanced scientific quality control. In summary, centralization of services clearly improves quality and efficiency in any large research operation, but importantly it reduces duplication of effort and competition for available resources, especially subjects. The initial funding period followed for the establishment of a well-defined Shared Scientific Resource Core. Leadership is strong, the access to the services has been clearly identified, and quality control is continuously monitored.

共享科学资源核心是在南卡罗来纳州医科大学酒精研究中心建立的，以促进酒精治疗研究的执行，提高研究效率，最大限度地利用资源，并通过标准化和集中化服务提供质量控制。所提供的核心服务是针对那些最有可能被几个项目利用的服务以及那些最适合集中的服务而量身定做的。在实现最初的具体目标方面取得了显著进展。在最初的几年里，雇用和培训了个人，建立了关键系统，并完善了服务组织。由此产生的系统运行顺利，核心服务被许多酒精研究人员利用，这些研究人员由中心赠款内外资助，对服务的需求继续增长。通过鼓励各项目共同努力，加强了沟通，建立了一个团结的工作单位，数据库管理效率高，生产率也有所提高。此次更新申请建议延续原有的三个具体目标，并增加一个新目标。持续的具体目标是：1）继续提供集中的主观招募和筛选; 2）继续提供集中的药房、医疗和实验室服务; 3）继续提供统计和数据库管理服务。新的目标，即具体目标4，是开发和提供集中的研究助理培训。后一个目标代表了我们的集中职能的自然延伸，预计将导致研究之间的更一致性，并加强科学质量控制。总而言之，服务的集中化明显提高了任何大型研究活动的质量和效率，但重要的是，它减少了重复劳动和对可用资源的竞争，特别是受试者。最初的资助期之后，建立了一个定义明确的共享科学资源核心。领导力强，服务的获取得到了明确的确定，质量控制得到了持续的监测。