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CORE--VECTOR PRODUCTION

CORE--VECTOR PRODUCTION
核心——矢量制作
批准号：
6652845
负责人：
Arthur Dusty Miller
金额：
$20.94万
依托单位：
FRED HUTCHINSON CANCER RESEARCH CENTER
依托单位国家：
美国
项目类别：
财政年份：
2002
资助国家：
美国
项目状态：
已结题
起止时间：
2002-09-01 至 2003-08-31
来源：
https://reporter.nih.gov/project-details/6652845
关键词：
Retroviridae biomedical facility biotechnology gene therapy transfection /expression vector

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中文摘要
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英文摘要
The overall function of the Vector Core is to provide high quality retroviral vectors, including lentiviral vectors, to investigators of this SCOR grant. Many of the projects in this SCOR proposal utilize retroviral vectors as experimental tools to introduce specific genes into hematopoietic cells and other cultured cells. The Vector Core will provide different vector plasmids and packaging cell lines as well as inappropriate technical support relating to the best vectors to use for specific studies. The Vector Core will provide large quantities of vectors required for the baboon studies in Project 6, and will produce these vectors in a dedicated facility under conditions similar to those used for production of vectors for human use. The facilities of the Vector Core can be used by other investigators or Vector Core staff to generate vector-producing cells suitable for human use. Issues of the potential for production of replication-competent viruses will be addressed, and assays for such viruses will be performed for clinical trials and for vectors used in laboratory studies. Safety or toxicity assays that cannot be performed in the Core will be contracted to outside laboratories as needed.
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Pilot and Feasibility Program
  • 批准号：
    7337073
  • 项目类别：
  • 资助金额：
    $15.69万
  • 财政年份：
    2007
  • 负责人：
    Arthur Dusty Miller
  • 依托单位：
    UNIVERSITY OF WASHINGTON
Administrative Core
  • 批准号：
    7499939
  • 项目类别：
  • 资助金额：
    $7.69万
  • 财政年份：
    2007
  • 负责人：
    Arthur Dusty Miller
  • 依托单位：
    UNIVERSITY OF WASHINGTON
Core--Retroviral and AAV Vector
  • 批准号：
    7337074
  • 项目类别：
  • 资助金额：
    $15.81万
  • 财政年份：
    2007
  • 负责人：
    Arthur Dusty Miller
  • 依托单位：
    UNIVERSITY OF WASHINGTON
Gene Therapy for Cystic Fibrosis Using AAV Vectors
  • 批准号：
    7154572
  • 项目类别：
  • 资助金额：
    $49.25万
  • 财政年份：
    2005
  • 负责人：
    Arthur Dusty Miller
  • 依托单位：
    UNIVERSITY OF WASHINGTON
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