Core--Aquatic Toxicology

核心--水生毒理学

• 批准号: 6664572
• 负责人: EVAN P GALLAGHER
• 金额: $ 13.16万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-25 至 2003-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6664572
• 关键词: animal colony; aquatic organism; biomedical facility; environmental toxicology; fish; hazardous substances; water pollution

The Aquatic Toxicology Core Facility provides technical expertise and facilities for the rearing, holding and toxicological testing of aquatic organisms. The aquatic core facility was completed in 1999 through funding from the University of Florida's College of Veterinary Medicine and Institute for Food and Agricultural Sciences, and currently operates on a cost-recovery basis. The incentive for establishment of the aquatic facility was based upon the extensive research efforts in aquatic toxicology form a number of University of Florida researchers and the lack of other aquatic toxicology facilities available. Accordingly, financial support for this core is essential for the successful completion of those projects which involving holding and toxicant dosing of aquatic animals, including project #1 (Drs. Denslow and Gallagher), project #2 (Drs. Schoeb and Gross), and project #6 (Drs. James and Kleinow). The specific aims of the core are 1) to provide Superfund investigators with technical assistance and consultation during all aquatic experiments involving the rearing, husbandry and dosing of aquatic organisms, and 2) to provide a physical environment for carrying out aquatic toxicological studies pertinent to the Superfund Program project grant. The aquatic core facility has the capability to house multiple aquatic species and to conduct acute and chronic studies. Project investigators will work with the aquatic core manager in the design and execution of all in vivo aquatic studies. A maximum amount of flexibility has been designed into the facility, allowing the facilities to be adapted to an investigator's needs. The facility is supplied with dechlorinated city water at a maximum rate of 20,000 gpm and three-1hp regenerative blowers at a maximum rate of 70 cfm supply aeration throughout the facility. All effluent is removed via a central drain system. Included as a service of the facility is an evaluation of the investigator's protocols by the ATD advisory board. This board approves projects to be conducted with in the facility and makes suggestions concerning animal husbandry and effluent discharge. The facility also has trained staff to perform water quality analysis and disease diagnosis and treatment.

水生毒理学核心设施为水生生物的饲养、饲养和毒理测试提供技术专门知识和设施。水产核心设施于1999年在佛罗里达大学兽医学院和食品与农业科学研究所的资助下建成，目前在成本回收的基础上运营。建立水生设施的动机是基于佛罗里达大学的一些研究人员在水生毒理学方面的广泛研究努力，以及缺乏其他可用的水生毒理设施。因此，对这一核心的财政支持对于成功完成涉及扣留和投毒水生动物的项目至关重要，这些项目包括项目1(Denslow和Gallagher博士)、项目2(Schoeb和Gross博士)和项目6(James和Kleinow博士)。该中心的具体目标是：1)在涉及水生生物饲养、饲养和投药的所有水生实验期间，为超级基金调查人员提供技术援助和咨询；2)为开展与超级基金计划项目拨款有关的水生毒理学研究提供物理环境。水生核心设施有能力容纳多种水生物种，并进行急性和慢性研究。项目调查人员将与水生核心经理合作，设计和执行所有活体水生研究。该设施设计了最大限度的灵活性，允许设施根据调查人员的需求进行调整。该设施提供最大速率为20,000 GPM的脱氯城市水和3-1马力的蓄热式鼓风机，最大速率为70 CFM，在整个设施内提供曝气。所有流出物都通过中央排水系统排出。作为该设施的一项服务，ATD顾问委员会对调查员的方案进行评估。该委员会批准在该设施内进行的项目，并就畜牧业和污水排放提出建议。该设施还培训了工作人员进行水质分析和疾病诊断和治疗。