HEALTH PROMOTION AND QUALITY OF LIFE CHRONIC ILLNESS

促进健康和生活质量 慢性病

• 批准号: 6627614
• 负责人: Alexa Stuifbergen
• 金额: $ 14.93万
• 依托单位: UNIVERSITY OF TEXAS AT AUSTIN
• 依托单位国家: 美国
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-09-30 至 2005-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6627614
• 关键词: behavioral /social science research tag; chronic disease /disorder; clinical research; degenerative motor system disease; disabling disease; health behavior; health education; human subject; longitudinal human study; medical rehabilitation related tag; multiple sclerosis; neural degeneration; nursing intervention; nursing models; outcomes research; patient care management; poliomyelitis; quality of life; rural area; urban area

Chronic disabling conditions have profound and pervasive effects on the lives of millions of Americans. Although rarely addressed, the need for health promotion continues to exist and may be accentuated in persons living with long-term, incurable conditions. The purpose of this five year competing continuation is to add depth to knowledge about health promotion in chronic disabling conditions by incorporation a longitudinal follow-up of the existing sample of rural and urban persons with multiple sclerosis (MS), integrating additional outcome measures. It will also expand knowledge of health promotion and quality of life among persons with chronic neurodegenerative conditions through validation of the explanatory model refined in the present study in a population of persons with a different chronic condition, post-polio syndrome. The specific aims are to (1) Conduct a longitudinal follow-up of persons in the current project to examine the effects of time and the trajectory of illness-related disability on a range of quality of life outcomes (perceived quality of life, employment, depression, and secondary disabilities); (2) Examine the influence of health promoting behaviors, barriers, and resources on individual change trajectories over multiple points in time, when controlling for the effects of illness-related disability; and (3) Validate and refine the explanatory model of health promotion and quality of life developed in the current study with an additional chronic disease population, persons with post-polio syndrome. A five year follow-up of the existing sample of persons with MS (N=759) is proposed; only 5% of the sample has been lost to follow-up at 2 years and 90% responded to a Time 2 questionnaire. A second sample of persons with post-polio (N=500) will be recruited. Instruments and data collection procedures refined in the present study will be incorporated in the continuation. Longitudinal data will be analyzed with hierarchical linear models (HLM) and event history analysis. Structural equation modeling (SEM) techniques will be used to validate and refine the model in the post-polio group. Information from this study will be used to design nursing interventions for persons with chronic neurodegenerative conditions.

慢性致残状况对身体产生深远而普遍的影响 数百万美国人的生活。尽管很少被提及，但需要 健康促进仍然存在，并可能在人身上得到加强 长期生活在无法治愈的状况下。这五年的目标 竞争性的延续是增加健康促进知识的深度 在慢性致残情况下，通过纳入纵向随访 农村和城市多发性硬化症患者的现有样本 （MS），整合额外的结果测量。也将扩大 患有此类疾病的人的健康促进和生活质量知识 通过验证解释性的慢性神经退行性疾病 本研究在一群患有以下疾病的人群中完善了模型 不同的慢性病，​​脊髓灰质炎后综合症。具体目标是 （1）对本项目人员进行纵向跟踪， 检查时间的影响和疾病相关的轨迹 残疾对一系列生活质量结果（感知的生活质量 生活、就业、抑郁和继发性残疾）； (2) 检查 健康促进行为、障碍和资源对健康的影响 个体在多个时间点上的变化轨迹，当 控制与疾病相关的残疾的影响；和（3） 验证和完善健康促进和质量的解释模型 当前研究中患有其他慢性疾病的生命发展 人口，患有脊髓灰质炎后综合症的人。 对现有多发性硬化症患者样本 (N=759) 进行的五年随访如下： 建议的;仅 5% 的样本在 2 年后失访 90% 的人回答了 Time 2 调查问卷。第二个样本的人 将招募脊髓灰质炎后患者（N=500）。仪器和数据采集 本研究中完善的程序将纳入 继续。纵向数据将采用分层线性分析 模型（HLM）和事件历史分析。结构方程建模 （SEM）技术将用于验证和完善模型 后脊髓灰质炎组。这项研究的信息将用于设计 慢性神经退行性疾病患者的护理干预 状况。