CORE--CELLULAR NEUROSCIENCE FACILITY

描述：细胞神经科学核心是从以前的 组织学和电子显微镜核心。组织学核心起源于 理查德·西德曼博士的领导和酋长的支持 技术专家，彼得·迪克斯先生。电子显微镜核心启动 在Hannah Kinney博士的领导下，他是第一任主任。 结合细胞神经科学核心 现任主任加布里埃尔·科法斯博士已经不再强调电子 显微镜方面的服务，有利于提供更广泛，高 更好地满足37名调查员当前需求的吞吐量服务 经常使用这个核心。这些用于结构化的组织制备方法 和分子解剖学检查，包括准备组织， 标准组织学，电子显微镜，共聚焦显微镜，原位 杂交和免疫细胞化学。此外，该核心还提供 灌注啮齿动物用于组织检查。 核心的一个重点是培训中心的调查人员及其同事 在组织制备方法中。细胞神经科学核心也 为研究者提供形态学和神经病理学咨询。 工作人员包括拥有35年经验的首席技术专家， 一个没什么经验的技术专家

DESCRIPTION: The Cellular Neuroscience Core was formed from the previous Histology and Electron Microscopy Cores. The Histology Core originated under the leadership of Dr. Richard Sidman, with support from the Chief Technologist, Mr. Pieter Dikkes. The Electron Microscopy Core was initiated under the leadership of Dr. Hannah Kinney, who was the first Director of the combined Cellular Neuroscience core. The current director, Dr. Gabriel Corfas, has de-emphasized the electron microscopy aspect of the service in favor of providing more extensive, high throughput services that better meet the current needs of the 37 investigators routinely using this Core. These methods of tissue preparation for structural and molecular anatomical examination include preparation of tissues for standard histology, electron microscopy, confocal microscopy, in situ hybridization, and immunocytochemistry. In addition, this Core provides perfusion of rodents for tissue examination. An emphasis of the Core is to train Center investigators and their associates in methods of tissue preparation. The Cellular Neuroscience Core also provides morphological and neuropathological consultation to investigators. Staff includes the Chief Technologist with 35 years of experience, and a to-be-named technologist with less experience.