PRE&POST-DOCTORAL TRAINING IN NEPHROLOGY&HYPERTENSION

预

• 批准号: 6620265
• 负责人: RICHARD David JOHNSON
• 金额: $ 11.87万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6620265
• 关键词: PRE&POST; DOCTORAL; TRAINING; NEPHROLOGY&HYPERTENSION

DESCRIPTION(provided by applicant): The goal of the proposed research training program is to prepare trainees for a successful academic research career by providing expert and comprehensive mentoring in laboratory or clinical research pertinent to kidney disease. The program proposed in this application has the faculty expertise, infrastructure, and research opportunities to provide outstanding training. The training program is organized into five thematic administrative units designed to provide greater interdisciplinary collaboration, adminstrative cohesiveness, and enhance research opportunities for trainees: the Core Nephrology Unit; the Diabetes, Human Genetics, and Gene Therapy Unit; the Glomerulonephritis and Renal Immunology Unit; the Stem Cell and Developmental Biology Unit; and the Clinical Research Training Unit. The program has thirty training mentors from different basic and clinical departments; the number of faculty has been increased substantially to provide a greater scope, depth and opportunities for interdisciplinary research in the basic sciences to accommodate the increasingly complex and technologic nature of research and the need to have greater participation of the basic sciences in the training of M.D. basic science investigators in nephrology. The research encompassed by the training program is highly pertinent to normal renal physiology and kidney disease. It includes the physiology, molecular biology and cell biology of tubular epithelial cells ion transport, the biochemistry of signaling pathways in kidney epithelia, the cell biology of the calcium receptor and other G-protein coupled receptors in renal epithelia, the early gene response to oxidative renal injury, the biochemical basis of renal tubular injury, and the cell biology and biochemistry of vascular endothelium. The training program also broadly encompasses the immunology, genetics, glomerular inflammation, and epithelial stem cell differentiation. Trainees will have full access to the entire graduate school curriculum, The clinical investigation program includes offering trainees the opportunity to apply for and enroll in the K30 APPCI program, which provides rigorous training in clinical epidemiology, biostatistics, outcomes research, study resign and a mentored clinical research program. Trainees are required to participate in a weekly formal research conference as well as weekly research-in-progress conferences in which both trainees and mentors responsible for supervision of research present their research.

描述(由申请人提供)： 拟议的研究培训方案的目标是使受训人员为 通过提供专业和全面的专业知识，成功的学术研究生涯 指导与肾脏疾病相关的实验室或临床研究。这个 本申请中提出的计划具有教师专业知识、基础设施、 和研究机会，提供出众的培训。培训 该计划分为五个主题行政单位，旨在 提供更强的跨学科协作、管理凝聚力、 并增加受训人员的研究机会：核心肾病科； 糖尿病，人类遗传学和基因治疗单位；肾小球肾炎和 肾脏免疫科；干细胞和发育生物科；以及 临床研究训练组。该项目有30名来自 不同的基础和临床科室；教职员工人数一直是 大幅增加，以提供更大的广度、深度和机会 基础科学的跨学科研究，以适应 研究的复杂性和技术性越来越强，需要 加强基础科学在医学基础训练中的参与 肾脏病科学研究人员。培训所包含的研究内容 该计划与正常的肾脏生理和肾脏疾病高度相关。它 包括肾小管的生理学、分子生物学和细胞生物学 上皮细胞离子转运，信号通路的生物化学 肾上皮细胞、钙受体和其他G蛋白的细胞生物学 肾上皮细胞偶联受体与早期基因氧化反应 肾损伤、肾小管损伤的生化基础及细胞 血管内皮细胞生物学和生物化学。培训计划还包括 广泛包括免疫学、遗传学、肾小球炎症和 上皮干细胞分化。学员将有权完全访问 整个研究生院的课程，临床调查课程包括 为学员提供申请和注册K30 APPCI的机会 该计划提供严格的临床流行病学培训， 生物统计学、结果研究、研究辞职和临床指导研究 程序。学员被要求参加每周一次的正式研究。 会议以及每周进行中的研究会议，在这些会议上 负责监督研究的学员和导师介绍了他们的 研究。