PRE&POST-DOCTORAL TRAINING IN NEPHROLOGY&HYPERTENSION

预

• 批准号: 7100081
• 负责人: RICHARD David JOHNSON
• 金额: $ 9.58万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7100081
• 关键词: PRE&POST; DOCTORAL; TRAINING; NEPHROLOGY&HYPERTENSION

DESCRIPTION(provided by applicant): The goal of the proposed research training program is to prepare trainees for a successful academic research career by providing expert and comprehensive mentoring in laboratory or clinical research pertinent to kidney disease. The program proposed in this application has the faculty expertise, infrastructure, and research opportunities to provide outstanding training. The training program is organized into five thematic administrative units designed to provide greater interdisciplinary collaboration, adminstrative cohesiveness, and enhance research opportunities for trainees: the Core Nephrology Unit; the Diabetes, Human Genetics, and Gene Therapy Unit; the Glomerulonephritis and Renal Immunology Unit; the Stem Cell and Developmental Biology Unit; and the Clinical Research Training Unit. The program has thirty training mentors from different basic and clinical departments; the number of faculty has been increased substantially to provide a greater scope, depth and opportunities for interdisciplinary research in the basic sciences to accommodate the increasingly complex and technologic nature of research and the need to have greater participation of the basic sciences in the training of M.D. basic science investigators in nephrology. The research encompassed by the training program is highly pertinent to normal renal physiology and kidney disease. It includes the physiology, molecular biology and cell biology of tubular epithelial cells ion transport, the biochemistry of signaling pathways in kidney epithelia, the cell biology of the calcium receptor and other G-protein coupled receptors in renal epithelia, the early gene response to oxidative renal injury, the biochemical basis of renal tubular injury, and the cell biology and biochemistry of vascular endothelium. The training program also broadly encompasses the immunology, genetics, glomerular inflammation, and epithelial stem cell differentiation. Trainees will have full access to the entire graduate school curriculum, The clinical investigation program includes offering trainees the opportunity to apply for and enroll in the K30 APPCI program, which provides rigorous training in clinical epidemiology, biostatistics, outcomes research, study resign and a mentored clinical research program. Trainees are required to participate in a weekly formal research conference as well as weekly research-in-progress conferences in which both trainees and mentors responsible for supervision of research present their research.

描述（由申请人提供）： 拟议的研究培训计划的目标是为学员做好准备， 成功的学术研究生涯，提供专家和全面的 指导与肾脏疾病相关的实验室或临床研究。的 本申请中提出的计划具有教师专业知识，基础设施， 和研究机会，以提供出色的培训。培训 该计划分为五个主题行政单位，旨在 提供更大的跨学科合作，行政凝聚力， 并增加学员的研究机会：核心肾脏科; 糖尿病、人类遗传学和基因治疗单位;肾小球肾炎和 肾免疫学单位;干细胞和发育生物学单位;和 临床研究培训单位。该计划有30名培训导师， 不同的基础和临床部门;教师的数量已经 大幅度增加，以提供更大的范围，深度和机会， 基础科学的跨学科研究，以适应 研究的复杂性和技术性越来越强， 基础科学更多地参与医学博士的培训;基本 肾脏病学的科学研究者培训所涵盖的研究 该程序与正常肾脏生理学和肾脏疾病高度相关。它 包括肾小管的生理学、分子生物学和细胞生物学 上皮细胞的离子转运， 肾上皮细胞、钙受体和其他G蛋白的细胞生物学 偶联受体在肾上皮细胞，早期的基因反应，氧化 肾损伤、肾小管损伤的生化基础和细胞 血管内皮生物学和生物化学。培训计划还 广泛涵盖免疫学、遗传学、肾小球炎症， 上皮干细胞分化学员将有充分的机会进入 整个研究生院课程，临床研究项目包括 为学员提供申请和注册K30 APPCI的机会 该计划提供严格的临床流行病学培训， 生物统计学、结果研究、研究辞职和指导临床研究 程序.学员必须参加每周一次的正式研究 会议以及每周的研究进展会议，其中既 负责监督研究的学员和导师介绍了他们的 research.