Epigenetic hyperglycemic cell memory causes vascular complications in type 1 diabetes
Epigenetic hyperglycemic cell memory causes vascular complications in type 1 diabetes
表观遗传高血糖细胞记忆导致 1 型糖尿病血管并发症
批准号：
nhmrc : 526694
负责人：
Dr Stephen Tonna
金额：
$22.15万
依托单位国家：
澳大利亚
项目类别：
Early Career Fellowships
财政年份：
2009
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2009-01-01 至 2013-12-31
中文摘要
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英文摘要
This project seeks to identify how epigenetic change in response to hyperglycemia can cause vascular complications of diabetes, and how this contributes to “hyperglycemic memory”; a phenomena where cells may undergo gene modifications which increase risk to further complications later in a patients life. These studies are the first of their kind and will characterize the types of epigenetic change that can cause human disease.
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会议论文
Genetic risk factors for renal impairment in thin basement membrane nephropathy
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批准号：nhmrc : 310643
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项目类别：NHMRC Postgraduate Scholarships
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资助金额：$2.81万
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财政年份：2004
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负责人：Dr Stephen Tonna
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依托单位：
海外基金
