MECHANISMS OF CDH-ASSOCIATED PULMONARY HYPOPLASIA

CDH 相关肺发育不全的机制

• 批准号: 6654862
• 负责人: JAY J SCHNITZER
• 金额: $ 33.66万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-30 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6654862
• 关键词: biological models; biological signal transduction; congenital respiratory disorder; diaphragm; hernia; histogenesis; laboratory rat; lung; mitogen activated protein kinase; mutant; organ culture; retinoid binding proteins; sheep; vitamin A deficiency

项目成果

Decreased mitogen activated protein kinase activities in congenital diaphragmatic hernia-associated pulmonary hypoplasia.

先天性膈疝相关肺发育不全中丝裂原激活蛋白激酶活性降低。

• DOI: 10.1053/jpsu.2001.27029
• 发表时间: 2001
• 期刊: Journal of pediatric surgery
• 影响因子: 2.4
• 作者: Kling,DE;Narra,V;Islam,S;Kinane,TB;Alessandrini,A;Ercolani,L;Donahoe,PK;Schnitzer,JJ
• 通讯作者: Schnitzer,JJ

Retinoic acid-mediated differentiation protects against nitrofen-induced apoptosis.

• DOI: 10.1002/bdrb.20131
• 发表时间: 2007-10
• 期刊: Birth defects research. Part B, Developmental and reproductive toxicology
• 作者: J. Aidlen;P. Nazarey;T. Kinane;P. Donahoe;J. Schnitzer;D. E. Kling

Nitrofen induces a redox-dependent apoptosis associated with increased p38 activity in P19 teratocarcinoma cells.

• DOI: 10.1016/j.tiv.2004.04.010
• 发表时间: 2005-02
• 期刊: Toxicology in vitro : an international journal published in association with BIBRA
• 作者: D. E. Kling;J. Aidlen;J. Fisher;T. Kinane;P. Donahoe;J. Schnitzer

Control and regulation of pulmonary hypoplasia associated with congenital diaphragmatic hernia.

控制和调节与先天性膈疝相关的肺发育不全。

• DOI: 10.1053/j.sempedsurg.2003.09.006
• 发表时间: 2004
• 期刊: Seminars in pediatric surgery
• 影响因子: 1.7
• 作者: Schnitzer,JayJ