NEW ORLEANS ADOLESCENT MEDICINE TRIALS UNIT

新奥尔良青少年药物试验股将促进和支持青少年药物试验网络艾滋病毒/艾滋病干预措施的科学议程。由青少年护理团队、杜兰/路易斯安那州立大学/慈善儿童艾滋病线索小组和新奥尔良青少年艾滋病毒/艾滋病研究计划的成员组成的新奥尔良AMTU将拥有八年以上与感染艾滋病毒的青少年的临床经验，并参与了多中心临床研究网络。此外，合作机构已经有十多年的历史，通过为青少年和年轻人提供服务来接触社区中的青年。为支持该倡议呼吁开展广泛的支持性和直接干预研究，旨在对青少年和年轻人的艾滋病毒感染进行一级、二级和三级预防，将招募年轻人进入青年管理数据库，可以联系他们以获得临床试验的收益。这将得到支持，评估预防模式，如疫苗，评估预防健康，技能建设，以及为青年预防艾滋病毒的其他缓冲措施。目前正在开展的活动中正在开展探索有效措施以查明感染艾滋病毒的青年并将其与卫生保健联系起来的试验、利用青年免疫复原力的疗法、药物管理战略和支持坚持的方法，并将作为AMTU加以扩大。最后，预计将开展研究，调查艾滋病毒对青年的生活和决策的影响，以便采取干预措施，支持青年在不利环境下的复原力，并为病情严重且可能没有太多选择的青年制定救助方案。新奥尔良AMTU有个人和组织的能力来通知、指导和实施青少年医学领导小组提出的研究。此外，该AMTU将通过自身对科学议程的贡献，以及对社区工作的理解和对弱势群体、难以接触到青少年的工作的理解，加强青少年医学试验网络。

The New Orleans Adolescent Medicine Trails Unit will contribute to and support the scientific agenda of Adolescent Medicine Trails Network for HIV/AIDS Interventions. Composed of members of the adolescent care team, the Tulane/LSU/Charity Pediatric AIDS Trails Unit, and the New Orleans Adolescent HIV/AIDS Research Program, the New Orleans AMTU will have had more than eight years' clinical experience with HIV infected youth and participation in multi center clinical research networks. In addition, the collaborating agencies have more than ten-year history reaching out to youth in the community by building services for adolescents and young adults. In support of the initiative's call for a broad array of supporting and direct intervention studies aimed at the primary, secondary, and tertiary prevention of HIV infection in adolescents and young adults, young people will be recruited to a managerial database of youth who can be contacted for accrual to clinical trails. This will be supported that assess models of prevention such as vaccines, assess to prevention health, skill- building, and other buffers for youth against HIV. Trails exploring effective measures of identifying and linking HIV infected youth to health care, therapies that exploit the immunologic resilience of youth, drug management strategies, and methods of supporting adherence are being implemented in current activities and will be expanded as an AMTU. Finally, studies that investigate the impact of HIV on young people's lives and decision-making with a view to implementing interventions that support youth's resilience under adverse circumstances as well as interventions with salvage protocols for youth who are very ill and may not have many options, are anticipated. The New Orleans AMTU has the individual and organizational capacity to inform, guide, and implement studies proposed by an adolescent Medicine Leadership Group. In addition, this AMTU will strengthen the Adolescent Medicine Trails Network through its own contributions to the scientific agenda and to an understanding of community work and work with disadvantage, hard to reach adolescents.