Exploring the emergence of psychotic experiences using multimodal neuroimaging and mathematical modelling

使用多模式神经影像和数学建模探索精神病经历的出现

• 批准号: 2119709
• 金额: --
• 依托单位: CARDIFF UNIVERSITY
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2119709
• 关键词: Exploring; emergence; psychotic; experiences; using

The overall aim is to understand the computational and neurocognitive processes underlying the emergence of psychosis, and neurocognitive contributions to psychopathological risk. Psychotic disorders such as schizophrenia are among the most devastating mental health conditions and leading contributors to the global burden of disease. Psychotic symptoms involve a loss of contact with reality in the form delusions (false beliefs) and hallucinations (perceptual experiences in the absence of stimuli). Given the complexity of the processes underlying these symptoms, recent advances have often been driven by integrated, cross-disciplinary approaches using mathematical models, behavioural testing, and neuroimaging (1).

总体目标是了解精神病出现的计算和神经认知过程，以及神经认知对精神病理风险的贡献。精神分裂症等精神障碍是最具破坏性的精神健康状况之一，也是造成全球疾病负担的主要原因。精神病症状包括以妄想（错误信念）和幻觉（缺乏刺激的知觉体验）的形式与现实失去联系。鉴于这些症状背后的复杂过程，最近的进展通常是由综合的跨学科方法驱动的，包括数学模型、行为测试和神经影像学(1)。