Vascular Depression and Function in Older Latinos

老年拉丁裔的血管抑郁和功能

• 批准号: 6598317
• 负责人: Hector M Gonzalez
• 金额: $ 14.5万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6598317
• 关键词: Mexican Americans; behavioral /social science research tag; cerebrovascular disorders; clinical research; cognition disorders; depression; diabetes mellitus; disease /disorder proneness /risk; health care service availability; human subject; hypertension; longitudinal human study

DESCRIPTION (provided by applicant): Elevated depressive symptoms affect nearly 26 percent of older Mexican Americans, but very few (9.1 percent) receive treatment. Older Mexican Americans have high rates of diabetes (33 percent), hypertension (62 percent) and depressive symptoms, which are risks associated with cerebrovascular disease. High rates of cerebrovascular disease risks and low stroke prevention awareness among Latinos presents a looming public health problem as this large population continues to rapidly grow. Currently little is known about the course and progression of mostly untreated depression, particularly as it relates to cerebrovascular disease in this large and rapidly growing population. The overall goal of the proposed research plan is to develop and refine methods for a longitudinal, population-based study of depression and cerebrovascular disease and their association with cognitive and functional status of older Mexican Americans. The Sacramento Area Latino Study on Aging (SALSA) is a population-based, longitudinal cohort study of 1,789 older Latinos of primarily Mexican descent. SALSA has a representative sample, which makes it an especially valuable data source for studying the predictors of cognitive and functional impairment and decline that are associated with depression. The proposed study will address important research questions concerning depression and cerebrovascular disease risk factors among older Mexican Americans, while providing a vehicle for the career development of the candidate.

描述（由申请人提供）：抑郁症状升高影响了近26%的墨西哥裔美国老年人，但很少（9.1%）接受治疗。老年墨西哥裔美国人糖尿病（33%），高血压（62%）和抑郁症状的发病率很高，这些都是与脑血管疾病相关的风险。高脑血管疾病风险率和低中风预防意识的拉美裔人提出了一个迫在眉睫的公共卫生问题，因为这个庞大的人口继续迅速增长。目前对大多数未经治疗的抑郁症的病程和进展知之甚少，特别是在这个庞大且快速增长的人群中，它与脑血管疾病有关。拟议研究计划的总体目标是开发和完善抑郁症和脑血管疾病及其与老年墨西哥裔美国人认知和功能状态相关的纵向、基于人群的研究方法。萨克拉门托地区拉丁裔老龄化研究（SALSA）是一项基于人口的纵向队列研究，研究对象为1,789名主要为墨西哥裔的老年拉丁裔人。SALSA具有代表性的样本，这使得它成为研究与抑郁症相关的认知和功能障碍和衰退的预测因素的特别有价值的数据来源。拟议的研究将解决有关老年墨西哥裔美国人中抑郁症和脑血管疾病风险因素的重要研究问题，同时为候选人的职业发展提供工具。