Pediatric Oncology Clinical Research Training Program

描述(申请人提供)：儿科肿瘤学家的发展 而在临床研究方面训练有素的儿科肿瘤科护士 对继续在儿童治疗方面取得进展至关重要 癌症。本提案描述了一项儿科肿瘤学的临床研究 培训计划，由贝勒医学院德克萨斯州儿童医院开发 癌症中心，旨在提供正式的、全面的、 多学科临床研究教育计划将培训董事会 已完成三年奖学金的合格儿科肿瘤学家 博士生编写的本体护士的设计、实现和分析 临床研究试验的所有阶段。实习生将花费一部分时间 他们第一年参加了临床研究和核心课程 在那一年和第二年的剩余时间里(S)接受进一步的临床治疗 在五个专业培训路径中选择一个的研究性培训 (临床药理学、神经肿瘤学、细胞和基因疗法、白血病或 实体瘤)。这项经过精心指导的培训计划将利用 BCM资助的(NIH-K30奖项)临床科学家培训计划提供 一门全面的、讲授式的临床研究核心课程，将作为 在以下五个专门领域之一进行进一步培训的基础 研究。每个领域的研究经验都将被量身定做 以满足学员个人的长期研究目标。它将提供 实验室和临床导师的指导，同时提供深入的 接触临床研究过程中最重要的方面。 将指导学员进行临床试验设计、统计分析、 研究道德和监管要求和指南。此外, 在经验丰富的导师的指导下，学员将设计和执行 在各自的重点领域进行临床试验，并将从导师那里学习 为实现以下目标所需的独特交互、协作技能建模 成功开展有效的临床试验。因为完成培训的学员 这项计划将在他们的基础生物学和 特定的专业领域和翻译研究技能，它们将是 非常适合成为未来儿科肿瘤学临床研究的领导者。

DESCRIPTION (provided by applicant): The development of pediatric oncologists and pediatric oncology nurses who are highly trained in clinical research is essential for continued progress to be made in the treatment of childhood cancer. This proposal describes a Pediatric Oncology Clinical Research Training Program, developed by Baylor College of Medicine's Texas Children's Cancer Center, that is structured to provide a formal, comprehensive, multidisciplinary clinical research educational program that will train board eligible pediatric oncologists who have completed a three year fellowship and Ph.D.-prepared ontology nurses in the design, implementation and analysis of all phases of clinical research trials. Trainees will spend a portion of their first year participating in a core curriculum in clinical research and spend the remainder of that and subsequent year(s) receiving further clinical research training in their choice of one of five specialized training tracks (clinical pharmacology, neuro-oncology cell and gene therapy, leukemia or solid tumors). This carefully mentored training program will take advantage of BCM's funded (NIH-K30 award) Clinical Scientist Training Program to provide a comprehensive, didactic clinical research core curriculum that will serve as a foundation for further training within one of the five specialized areas of research. The research experience within each of these areas will be tailored to meet the individual trainee's long-term research goals. It will provide mentorship by both a laboratory and clinical mentor' while providing in depth exposure to the most important facets of the clinical research process. Trainees will be instructed in clinical trial design, statistical analysis, research ethics and regulatory requirements and guidelines. In addition, under the tutelage of experienced mentors, trainees will design and conduct clinical trials in their respective areas of focus and will learn by mentor modeling the uniquely interactive, collaborative skills necessary to successfully develop effective clinical trials. Because trainees who complete this program will be well-grounded in both in the basic biology of their particular specialty areas and translational research skills, they will be well suited to become future leaders in pediatric oncology clinical research.