Image Reconstruction with Solid State SPECT

使用固态 SPECT 进行图像重建

基本信息

  • 批准号:
    6616465
  • 负责人:
  • 金额:
    $ 19.88万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2003
  • 资助国家:
    美国
  • 起止时间:
    2003-03-17 至 2006-02-28
  • 项目状态:
    已结题

项目摘要

The main objective of this project is the development and evaluation of image reconstruction methods for a rotating, strip gamma camera for SPECT (single photon emission computed tomography). The strip gamma camera consists of a CdZnTe detector and a tungsten slat collimator. This solid-state detector is photomultiplier-tube free and has higher energy resolution (about 3% FWHM at 140 keV photopeak) than a regular Anger camera. In order to reduce the cost of CdZnTe material, the detector is a narrow rectangular strip. Instead of using a parallel-hole collimator, a set of parallel slats that define a series of planes are used to collimate the incoming photons. As a result, the measured projection data are planar integrals as opposed to the line integrals that are generally encountered in traditional Anger camera applications. The measured planar integral of the radioactivity distribution is weighted by a factor l/r, where r is the distance from the point of interest to the detector. One important goal of this proposal is to develop reconstruction algorithms that can exactly compensate for the detectors distance dependent sensitivity. Another important goal of this proposal is to develop algorithms that make the images immune from truncation errors. This will make our imaging system a local tomographic device. Still another important goal of this proposal is to evaluate the performance of the combination of the new detector and reconstruction algorithms. Special emphasis will be placed on developing a novel solid-state imaging system that will provide nearly scatter-free and truncation-error-free images. High image spatial resolution will be achieved by using convergent slat collimators. The work has the potential to significantly improve the diagnostic capabilities of SPECT imaging. This proposal will (a) promote the development of very novel (high risk, high gain) technologies, including continued support for their maturation and full exploitation, (b) promote system integration of technologies for targeted applications, and (c) improve technology transfer by promoting partnerships between academia and industry.
该项目的主要目标是开发和评价SPECT(单光子发射计算机断层扫描)旋转条形伽马相机的图像重建方法。条形γ相机由CdZnTe探测器和钨条准直器组成。这种固态探测器不含光电倍增管,并且具有比常规Anger相机更高的能量分辨率(在140 keV的峰值下约为3%的半高宽)。为了降低CdZnTe材料的成本,探测器采用窄矩形条。 代替使用平行孔准直器,一组定义一系列平面的平行板条被用于准直入射光子。因此,测量的投影数据是平面积分,而不是传统的Anger相机应用中通常遇到的线积分。测量的放射性分布的平面积分通过因子l/r加权,其中r是从感兴趣点到检测器的距离。这个建议的一个重要目标是开发重建算法,可以精确地补偿探测器的距离依赖的灵敏度。 该提案的另一个重要目标是开发算法,使图像免受截断误差的影响。这将使我们的成像系统成为一个局部断层成像设备。该提议的另一个重要目标是评估新检测器和重建算法的组合的性能。特别强调将放在开发一种新的固态成像系统,将提供几乎无散射和截断误差的图像。使用会聚板条准直器将获得高的图像空间分辨率。这项工作有可能显着提高SPECT成像的诊断能力。这项建议将(a)促进开发非常新颖的(高风险、高收益)技术,包括继续支持其成熟和充分利用,(B)促进针对目标应用的技术系统集成,(c)通过促进学术界和工业界之间的伙伴关系改进技术转让。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(3)

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G LAWRENCE ZENG其他文献

G LAWRENCE ZENG的其他文献

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{{ truncateString('G LAWRENCE ZENG', 18)}}的其他基金

Segmented-Parallel-Beam Stationary Cardiac SPECT
分段平行束固定心脏 SPECT
  • 批准号:
    8412762
  • 财政年份:
    2012
  • 资助金额:
    $ 19.88万
  • 项目类别:
Segmented-Parallel-Beam Stationary Cardiac SPECT
分段平行束固定心脏 SPECT
  • 批准号:
    8237814
  • 财政年份:
    2012
  • 资助金额:
    $ 19.88万
  • 项目类别:
Segmented-Parallel-Beam Stationary Cardiac SPECT
分段平行束固定心脏 SPECT
  • 批准号:
    8590221
  • 财政年份:
    2012
  • 资助金额:
    $ 19.88万
  • 项目类别:
Small Animal SPECT Using a Skew-Slit Collimator
使用斜缝准直器的小动物 SPECT
  • 批准号:
    7471761
  • 财政年份:
    2008
  • 资助金额:
    $ 19.88万
  • 项目类别:
Small Animal SPECT Using a Skew-Slit Collimator
使用斜缝准直器的小动物 SPECT
  • 批准号:
    7570636
  • 财政年份:
    2008
  • 资助金额:
    $ 19.88万
  • 项目类别:
Breast Cancer Imaging Using a Solid-State SPECT Camera
使用固态 SPECT 相机进行乳腺癌成像
  • 批准号:
    6672262
  • 财政年份:
    2003
  • 资助金额:
    $ 19.88万
  • 项目类别:
Radio-Immunotherapy (RIT) Planning Using SPECT
使用 SPECT 进行放射免疫治疗 (RIT) 规划
  • 批准号:
    6751152
  • 财政年份:
    2003
  • 资助金额:
    $ 19.88万
  • 项目类别:
Image Reconstruction with Solid Srate SPECR
使用 Solid Srate SPECR 进行图像重建
  • 批准号:
    6721473
  • 财政年份:
    2003
  • 资助金额:
    $ 19.88万
  • 项目类别:
Image Reconstruction with Solid Srate SPECR
使用 Solid Srate SPECR 进行图像重建
  • 批准号:
    6865474
  • 财政年份:
    2003
  • 资助金额:
    $ 19.88万
  • 项目类别:
Breast Cancer Imaging Using a Solid-State SPECT Camera
使用固态 SPECT 相机进行乳腺癌成像
  • 批准号:
    6782564
  • 财政年份:
    2003
  • 资助金额:
    $ 19.88万
  • 项目类别:
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