INIA: Informatics Core

INIA：信息学核心

• 批准号: 6622585
• 负责人: JAY R SNODDY
• 金额: $ 28.85万
• 依托单位: UNIVERSITY OF TENNESSEE KNOXVILLE
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-01-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6622585
• 关键词: Internet; alcoholism /alcohol abuse; biomedical facility; computer data analysis; computer system design /evaluation; cooperative study; data collection methodology /evaluation; data management; informatics; information dissemination; information systems; statistics /biometry; technology /technique development

DESCRIPTION (provided by applicant): The Informatics Core of the Integrative Neurosciences Initiative on Alcoholism (INIA) provides central informational and computational resources for the different INIA research projects and cores. This INIA informatics core will, first, provide the collaborative information management, information technologies, and databases that are critical for these INIA projects to acquire and manage their data. The informatics core will develop a number of collaborative information systems that should help break down the geographic barriers to scientific collaboration; this core will enable the evaluation and direct application of these information-technology-backed collaborative tools for use by MA researchers. For exploratory research, several electronic laboratory notebooks will be developed. In addition, web-accessible lab information systems will also be built for larger-scale data discovery projects that allow central tracking and sharing of very different kinds of phenotype data about the same mouse strain from different research labs and institutions. Secondly, this core will provide some computational analysis and data mining tools that should enable INIA researchers to sift through their data for interesting patterns, especially patterns that might suggest hypotheses that can be tested by further experiments. In addition, the core will help initiate and foster collaborations between experimental INIA researchers and other computational researchers that might not be directly funded by this project. Thirdly, this core needs to make the finished INIA information freely available to the entire community via database-backed web sites and promote interperability of its data with data from other projects. For the subset of data that a community database can accept, the informatics core will need to package and forward that data to them. This core will work with other informatics researchers and developers on common data schemas, domain ontologies, data formats, and other ways to promote interperability across different data and databases.

描述（由申请人提供）： 酗酒综合神经科学倡议的信息学核心 (INIA) 为以下领域提供中央信息和计算资源： 不同的 INIA 研究项目和核心。这个 INIA 信息学核心将， 一、提供协同信息管理、信息 对于这些 INIA 项目至关重要的技术和数据库 获取并管理他们的数据。信息学核心将开发一系列 协作信息系统应该有助于打破地理 科学合作的障碍；该核心将能够进行评估和 直接应用这些信息技术支持的协作工具 供 MA 研究人员使用。对于探索性研究，一些电子 将开发实验室笔记本。此外，可通过网络访问的实验室 还将建立信息系统以进行更大规模的数据发现 允许集中跟踪和共享非常不同类型的项目 来自不同研究实验室的同一小鼠品系的表型数据 机构。其次，该核心将提供一些计算分析和 数据挖掘工具应使 INIA 研究人员能够筛选他们的数据 有趣模式的数据，尤其是可能暗示的模式 可以通过进一步的实验来检验的假设。此外，核心 将帮助发起和促进实验性 INIA 之间的合作 研究人员和其他计算研究人员可能不会直接 由该项目资助。第三，这个核心需要制作成品INIA 通过数据库支持的网络向整个社区免费提供信息 网站并促进其数据与其他项目数据的互操作性。 对于社区数据库可以接受的数据子集，信息学 core 将需要打包这些数据并将其转发给他们。这个核心可以工作 与其他信息学研究人员和开发人员一起研究通用数据模式， 领域本体、数据格式和其他促进互操作性的方法 跨不同的数据和数据库。