Low cost, micro engineered platform for rapid bacteria diagnostics

用于快速细菌诊断的低成本微工程平台

• 批准号: 2243974
• 金额: --
• 依托单位: University College London
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2019
• 资助国家: 英国
• 起止时间: 2019 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2243974
• 关键词: Low; cost; micro; engineered; platform

The project aims at producing novel, low cost, point of care tools for the rapid detection of bacteria. The emphasis will be on early diagnosis and stratification of sepsis, a life threatening and poorly diagnosed condition affecting millions of people worldwide, however some of these developments can be applicable to other infections such as urine infections (UTIs). The project will draw on our expertise in microfluidic technologies and microscale blood flows to explore bacteria biophysics in confined flows, separation of bacteria from blood, development of smart and low-cost fluidic platforms and bio sensing technologies in order to enable rapid detection and analysis of bacteria and other biomarkers in bodily fluids (esp. blood) and antimicrobial resistance testing at the point-of-care.

该项目旨在生产新的、低成本的护理点工具，用于快速检测细菌。重点将放在脓毒症的早期诊断和分层上，这是一种威胁生命且诊断不佳的疾病，影响着全球数百万人，但其中一些进展可能适用于其他感染，如尿路感染(UTIs)。该项目将利用我们在微流控技术和微尺度血液流动方面的专业知识，探索受限流动中的细菌生物物理学，从血液中分离细菌，开发智能和低成本的流体平台和生物传感技术，以便能够快速检测和分析体液(特别是血液)中的细菌和其他生物标志物。血液)和护理地点的抗菌素耐药性测试。