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Core--Transgenic Animal Facility

Core--Transgenic Animal Facility
核心--转基因动物设施
批准号:
6825336
负责人:
PATRICIA D. HURN
金额:
$24.73万
依托单位国家:
美国
项目类别:
财政年份:
2003
资助国家:
美国
项目状态:
已结题
起止时间:
2003-09-30 至 2008-06-30

项目摘要

项目成果

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中文摘要
翻译
核心C是一个设施,旨在提供国家的最先进的小鼠饲养和殖民地管理和基因分型服务。其目标是:1)维持转基因和基因敲除小鼠品系的繁殖群体,包括雌激素受体、亚型α、基因敲除、cP 450雌激素芳香化酶基因敲除和两种性别的聚ADP核糖聚合酶(PARP)基因敲除;和2)通过标准基因分型筛选育种者、群体扩增和向项目内的项目供应动物。这个核心设施将是该计划的共享资源,并将在我们的调查中发挥核心作用, 实验性中风和心脏骤停
英文摘要
Core C is a facility designed to provide state-of-the-art mouse husbandry and colony management and a genotyping service. Its aims are: 1) To maintain breeding colonies of transgenic and knockout mouse lines, including estrogen receptor, subtype alpha, knockouts, cP450 estrogen aromatase knockouts, and poly-ADP ribose polymerase (PARP) knockouts of both sexes; and 2) To screen via standard genotyping for selection of breeders, for colony expansion and for supply of animals to projects within the program. This core facility will be a shared resource of the program and will play a central role in our investigations of experimental stroke and cardiac arrest.
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国内基金
海外基金
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  • 批准号:
    19ZR1452900
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2019
  • 负责人:
    史仍飞
  • 依托单位: