Integrated and Translational Training in Anesthesiology Research

麻醉学研究的综合转化培训

• 批准号: 7645027
• 负责人: PATRICIA D. HURN
• 金额: $ 11.87万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7645027
• 关键词: Anesthesiology; Research; Training

DESCRIPTION (provided by applicant): Over the past 40 years, anesthesiologists have become increasingly important contributors to both basic science and clinical research. To be effective, this research has required an increased understanding of basic physiology, pharmacology, genetics, molecular biology, bioengineering, epidemiology, and biostatistics. If anesthesiology is to continue to improve the safety of care provided to an increasingly complicated group of patients of increasing age and to continue to attract the most competent care providers into the specialty, we must provide the best training possible, both in clinical care and research. We believe it is crucial to maintain training of anesthesiologists as scientists in order to maintain the clinical relevance of research endeavors. The rapid progression of scientific discovery in recent years, offers remarkable opportunities for direct application of basic scientific findings to patients with disease. Rigorous training in both basic science and clinical research is the key to optimize this type of translational research. The goal of this program is to provide basic and clinical scientific training to academic anesthesiologists as an integral component of their postgraduate clinical training program. This training will allow anesthesiologists to establish independent investigative careers devoted to improving care of the anesthetized/critically ill patient by advancing knowledge in the field. This proposal outlines the credentials of a diverse but cohesive faculty who are willing and prepared to meet this objective. The training program involves a two year continuum where trainees work under close supervision of a faculty member in research areas of neuroscience, gender biology, lung biology, cardiovascular, kidney, metabolism, and pain. Initially, the trainee will learn research skills, and later emphasis will be directed towards independent hypothesis generation, experimental design, data analysis, presentation of research findings, and competition for external funding. Research opportunities are offered by faculty members with proven records of success in the training of postdoctoral fellows, both from within Anesthesiology as well as from other collaborating basic science and clinical departments: neurology, medicine, neuroscience, pediatrics, neurosurgery, pathology, and physiology & pharmacology. This program is designed to produce academic anesthesiologists who will provide academic leadership throughout this century.

描述（由申请人提供）：在过去的 40 年里，麻醉师对基础科学和临床研究做出了越来越重要的贡献。为了发挥作用，这项研究需要加深对基础生理学、药理学、遗传学、分子生物学、生物工程、流行病学和生物统计学的了解。如果麻醉学要继续提高为日益复杂的年龄增长的患者群体提供护理的安全性，并继续吸引最有能力的护理人员进入该专业，我们必须在临床护理和研究方面提供尽可能最好的培训。我们认为，维持麻醉师作为科学家的培训对于保持研究工作的临床相关性至关重要。近年来科学发现的快速发展为将基础科学发现直接应用于疾病患者提供了绝佳的机会。基础科学和临床研究方面的严格培训是优化此类转化研究的关键。该计划的目标是为学术麻醉师提供基础和临床科学培训，作为其研究生临床培训计划的组成部分。该培训将使麻醉师能够建立独立的研究职业，致力于通过推进该领域的知识来改善对麻醉/危重患者的护理。该提案概述了愿意并准备实现这一目标的多元化但有凝聚力的教师的资历。该培训计划为期两年，学员在神经科学、性别生物学、肺生物学、心血管、肾脏、新陈代谢和疼痛研究领域的教员的密切监督下工作。最初，学员将学习研究技能，随后的重点将是独立的假设生成、实验设计、数据分析、研究成果的展示以及外部资金的竞争。研究机会由在博士后培训方面拥有成功记录的教职人员提供，这些教职人员来自麻醉学内部以及其他合作的基础科学和临床部门：神经病学、医学、神经科学、儿科、神经外科、病理学以及生理学和药理学。该项目旨在培养学术麻醉师，他们将在整个世纪提供学术领导力。