CVD Risk Factors and Sexual Identity in Women

女性心血管疾病危险因素和性别认同

• 批准号: 6574118
• 负责人: DEBORAH J AARON
• 金额: $ 64.8万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-03-05 至 2007-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6574118
• 关键词: behavioral /social science research tag; cardiovascular disorder risk; clinical research; female; health behavior; homosexuals; human subject; identity; lifestyle; sex behavior; women's health

DESCRIPTION (provided by applicant): Coronary heart disease (CHD) is the leading cause of mortality among women living in the United States, regardless of race and ethnicity and is likely the leading cause of mortality among lesbians. However, in various reports since 1994, the National Institute of Mental Health, the Centers for Disease Control and Prevention, the American MedicalAssociation, the American Public Health Association, and the Institute of Medicine (IOM) have pointed out that health care and health research affecting lesbian women are inadequate. As women, lesbians share many of the same health concerns of all women. However, as emphasized in the IOM Report on Lesbian Health "factors assumed to place women at risk for or to protect them against health disorders may not be present at the same levels or operate in the same way for lesbians". The IOM report also recognizes that "women who self-identify as lesbian may also experience stressors not commonly faced by heterosexual women" and that "it is important to understand the factors that areunique to lesbians and their impact on lesbians' health". Data which do exist from household surveys and studies utilizing convenience samples indicate that women who identify as lesbian may differ from heterosexual women in several important factors which contribute to the development of CHD. However, to date there has not been a comprehensive examination of CHD risk in a large sample of women who identify as lesbian or an examination of how their pattern of risk factors or overall risk for CHD may differ from a sample of demographically similar heterosexual women. The overall goal of this project is to examine potential differences in the prevalence and pattern of risk factors for CHD in a sample of 500 self-identified lesbians and 500 heterosexual women, matched for age, socioeconomic status, and ethnicity. A secondary goal of this project is to determine if lesbians are at increased risk of CHD using a standardized risk model. Specifically, 1. We will test the hypotheses that the prevalence and pattern of CHD risk factors are different between lesbians and heterosexual women. 2. We will determine the absolute and relative risk estimates for CHD based on the Framingham multiple-risk-factor assessment equations, and test the hypothesis that lesbians are at increased risk of CHD compared to heterosexual women.

描述（由申请人提供）：冠心病（CHD）是生活在美国的女性死亡的主要原因，无论种族和民族如何，并且可能是女同性恋者死亡的主要原因。然而，在1994年以来的各种报告中，国家精神卫生研究所、疾病控制和预防中心、美国医学协会、美国公共卫生协会和医学研究所（IOM）都指出，影响女同性恋者的保健和健康研究不足。作为女性，女同性恋者与所有女性有许多相同的健康问题。然而，正如国际移民组织关于女同性恋者健康的报告所强调的，"假定使妇女面临健康障碍风险或保护她们免受健康障碍影响的因素可能并不存在于女同性恋者身上，或以同样的方式发挥作用"。国际移民组织的报告还认识到，"自认为是女同性恋的妇女也可能经历异性恋妇女不常面临的压力"，"重要的是要了解女同性恋特有的因素及其对女同性恋健康的影响"。从家庭调查和利用便利样本的研究中确实存在的数据表明，被认定为女同性恋的妇女在导致冠心病发展的几个重要因素上可能与异性恋妇女不同。然而，到目前为止，还没有一个全面的检查冠心病的风险，在一个大样本的妇女谁确定为女同性恋或检查他们的模式的危险因素或冠心病的整体风险可能会有所不同，从一个样本的人口统计学上相似的异性恋妇女。该项目的总体目标是在500名自我认定的女同性恋者和500名异性恋妇女的样本中，研究冠心病危险因素的患病率和模式的潜在差异，这些样本在年龄、社会经济地位和种族方面相匹配。该项目的第二个目标是使用标准化风险模型确定女同性恋者是否有冠心病的风险增加。具体地说， 1.我们将测试的假设，冠心病危险因素的患病率和模式是不同的女同性恋和异性恋妇女。 2.我们将根据Frachial多危险因素评估方程确定CHD的绝对和相对风险估计值，并检验女同性恋者与异性恋女性相比CHD风险增加的假设。