课题基金 / 基金详情

SURGICAL STUDIES OF GI PEPTIDES--MECHANISMS OF ACTION

SURGICAL STUDIES OF GI PEPTIDES--MECHANISMS OF ACTION
胃肠道肽的外科研究——作用机制
批准号：
6524192
负责人：
Courtney M Townsend
金额：
$41.68万
依托单位：
UNIVERSITY OF TEXAS MED BR GALVESTON
依托单位国家：
美国
项目类别：
财政年份：
1994
资助国家：
美国
项目状态：
已结题
起止时间：
1994-08-01 至 2003-07-31
来源：
https://reporter.nih.gov/project-details/6524192
关键词：
G protein biological signal transduction cell growth regulation cell proliferation gastrins gastrointestinal neoplasms hormone receptor hormone regulation /control mechanism human tissue in situ hybridization molecular oncology polymerase chain reaction protein localization protein tyrosine kinase receptor binding receptor expression

项目摘要

项目成果

Courtney M Townsend的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
DESCRIPTION: GI peptides are ubiquitous substances, many of which are trophic for epithelial cell growth and development. These peptides modulate their effects after binding to specific receptors. Although there is some cross reactivity, the emergence and characterizations of unique receptors may provide better understanding into control of cellular proliferation. This proposal serves to characterize a unique gastrin associated receptor, G/G-Gly R, which appears to be distinct from the CCK-B receptor in its specificity and action. Better understanding of this receptor and its location, as well as mechanisms for cellular proliferation may allow the use of novel non-toxic forms of anti-neoplastic therapy in GI tract cancers.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
ROLE OF MITOGEN-ACTIVATED PROTEIN KINASES IN GI PEPTIDE HORMONE RECEPTOR SIGNALIN
GI HORMONES IN NORMAL AND NEOPLASTIC GUT AND PANCREAS
GI HORMONES IN NORMAL AND NEOPLASTIC GUT AND PANCREAS
CORE--TISSUE CULTURE
海外基金