Vanderbilt Center for Education/Research on Theraputics

描述：(由申请人提供)：范德比尔特治疗教育和研究中心(CERT)的继续存在是为了系统地改善药物治疗的国家合作的一部分。Vanderbilt CERT的主题是鼓励医疗补助和退伍军人健康管理局群体的最佳治疗，这两个群体特别容易受到次优药物治疗的影响，由于各种原因在研究中代表性不足，并受到可能对治疗产生不利影响的管理保健政策的影响。CERT重点关注的弱势群体包括发育中的胎儿、幼儿、低收入母亲、非裔美国人和其他少数群体、有精神和躯体残疾的人、慢性病患者、老年人和养老院的人。Vanderbilt CERT通过与我们的合作伙伴合作开展跨学科项目来实现其使命，这些项目有以下4个具体目标： 1.通过对药物效果的研究来改善治疗学的知识库；2.找出不太理想的提供者或患者的治疗实践；3.开展有针对性的教育计划，以改进治疗学；4.评估可能影响治疗学的医疗保健支付者政策的影响。 在最初的三年里，范德比尔特CERT建立了一个行政基础设施，组织了4个专题调查小组，并发展了一个由12名教员组成的合作网络。它与田纳西州、田纳西州质量改进组织、退伍军人管理局、田纳西州山谷医疗系统和老年研究、教育和临床中心以及食品和药物管理局建立了牢固的合作伙伴关系。它开展了25个核心项目，迄今已出版14份出版物、7份正在审查的手稿和4份正在编写中的出版物；并拥有51份杠杆出版物。 在即将到来的周期中，中心将开展10个核心项目和3个面向伙伴的教育外联/服务活动。这些多学科项目包括7项研究，旨在为临床争议领域的提供者和患者决策提供信息，以及3项教育计划，这些计划以循证指南为基础，旨在减少护理中的不适当差异。这些项目包括妇女、少数族裔和儿童的大量代表；并将重点放在对医疗补助、医疗保险和其他联邦医疗计划重要的高成本疾病州。

DESCRIPTION: (PROVIDED BY APPLICANT):Continuation of the Vanderbilt Center for Education and Research in Therapeutics (CERT) is proposed as part of a national collaboration to systematically improve pharmacotherapy. The theme of the Vanderbilt CERT is Encouraging Optimal Therapeutics in Medicaid and Veteran's Health Administration Populations, populations particularly vulnerable to suboptimal pharmacotherapy, underrepresented in research for a variety of reasons, and affected by managed care policies that may adversely affect therapeutics. Vulnerable groups encompassed by the CERT focus include the developing fetus, young children, low-income mothers, African Americans and other minorities, persons with mental and somatic disabilities, the chronically ill, the elderly, and persons in nursing homes. The Vanderbilt CERT realizes its mission by conducting interdisciplinary projects in conjunction with our partners that have the following 4 specific aims: 1. Improve the knowledge base for therapeutics by conducting studies of drug effects;2. Identify suboptimal provider or patient therapeutic practices;3. Conduct focused educational programs to improve therapeutics;4. Evaluate the impact of health care payer policies that may affect therapeutics. In its first three years, the Vanderbilt CERT has created an administrative infrastructure, organized 4 thematic investigator groups, and developed a collaborative network with 12 faculty. It has established strong partnerships with the State of Tennessee, the Tennessee Quality Improvement Organization, the Veteran's Administration Tennessee Valley Healthcare System and Geriatric Research, Education and Clinical Center, and the Food and Drug Administration. It has conducted 25 core projects that to date have resulted in 14 publications, 7 manuscripts under review, and 4 in preparation; and has 51 leveraged publications. In the upcoming cycle, the CERT will conduct 10 core projects and 3 partner-oriented, educational outreach/service activities. The multi-disciplinary projects include 7 research studies designed to inform provider and patient decision making in areas of clinical controversy and 3 educational programs underpinned by evidence-based guidelines and designed to reduce inappropriate variations in care. The projects include substantial representation of women, minorities, and children; and focus on high-cost disease states that are important to Medicaid, Medicare, and other federal health programs.