Vanderbilt Center for Education/Research on Theraputics

产品说明：（由申请人提供）：继续范德比尔特治疗学教育和研究中心（CERT）的建议，作为国家合作的一部分，以系统地改善药物治疗。 范德比尔特CERT的主题是鼓励医疗补助和退伍军人健康管理局人群的最佳治疗，这些人群特别容易受到次优药物治疗的影响，由于各种原因在研究中代表性不足，并受到可能对治疗产生不利影响的管理式护理政策的影响。应急小组重点关注的弱势群体包括发育中的胎儿、幼儿、低收入母亲、非裔美国人和其他少数民族、精神和身体残疾者、慢性病患者、老年人和养老院的人。 范德比尔特CERT通过与我们的合作伙伴一起开展跨学科项目来实现其使命，这些项目具有以下4个具体目标： 1. 通过开展药物效应研究，改善治疗学知识基础;2. 确定次优供应商或患者的治疗实践;3. 开展有针对性的教育计划，以改善治疗;4。 评估可能影响治疗的医疗保健支付者政策的影响。 在最初的三年里，范德比尔特CERT创建了一个行政基础设施，组织了4个专题研究小组，并与12名教师建立了合作网络。 它与田纳西州，田纳西州质量改进组织，退伍军人管理局田纳西流域医疗保健系统和老年医学研究，教育和临床中心以及食品和药物管理局建立了强有力的合作伙伴关系。它开展了25个核心项目，迄今已产生14份出版物，7份手稿正在审查，4份正在编写;并有51份杠杆出版物。 在下一个周期，应急小组将开展10个核心项目和3个面向伙伴的教育外联/服务活动。 这些多学科项目包括7项研究，旨在为临床争议领域的提供者和患者决策提供信息，以及3个以循证指南为基础的教育项目，旨在减少护理中的不当变化。 这些项目包括妇女、少数民族和儿童的大量代表;并重点关注对医疗补助、医疗保险和其他联邦卫生计划很重要的高成本疾病州。

DESCRIPTION: (PROVIDED BY APPLICANT):Continuation of the Vanderbilt Center for Education and Research in Therapeutics (CERT) is proposed as part of a national collaboration to systematically improve pharmacotherapy. The theme of the Vanderbilt CERT is Encouraging Optimal Therapeutics in Medicaid and Veteran's Health Administration Populations, populations particularly vulnerable to suboptimal pharmacotherapy, underrepresented in research for a variety of reasons, and affected by managed care policies that may adversely affect therapeutics. Vulnerable groups encompassed by the CERT focus include the developing fetus, young children, low-income mothers, African Americans and other minorities, persons with mental and somatic disabilities, the chronically ill, the elderly, and persons in nursing homes. The Vanderbilt CERT realizes its mission by conducting interdisciplinary projects in conjunction with our partners that have the following 4 specific aims: 1. Improve the knowledge base for therapeutics by conducting studies of drug effects;2. Identify suboptimal provider or patient therapeutic practices;3. Conduct focused educational programs to improve therapeutics;4. Evaluate the impact of health care payer policies that may affect therapeutics. In its first three years, the Vanderbilt CERT has created an administrative infrastructure, organized 4 thematic investigator groups, and developed a collaborative network with 12 faculty. It has established strong partnerships with the State of Tennessee, the Tennessee Quality Improvement Organization, the Veteran's Administration Tennessee Valley Healthcare System and Geriatric Research, Education and Clinical Center, and the Food and Drug Administration. It has conducted 25 core projects that to date have resulted in 14 publications, 7 manuscripts under review, and 4 in preparation; and has 51 leveraged publications. In the upcoming cycle, the CERT will conduct 10 core projects and 3 partner-oriented, educational outreach/service activities. The multi-disciplinary projects include 7 research studies designed to inform provider and patient decision making in areas of clinical controversy and 3 educational programs underpinned by evidence-based guidelines and designed to reduce inappropriate variations in care. The projects include substantial representation of women, minorities, and children; and focus on high-cost disease states that are important to Medicaid, Medicare, and other federal health programs.