Medical Image Processing Using Optical Fourier Technique
使用光学傅里叶技术的医学图像处理
基本信息
- 批准号:6644794
- 负责人:
- 金额:$ 19.24万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2002
- 资助国家:美国
- 起止时间:2002-08-13 至 2005-07-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
DESCRIPTION (provided by applicant): The ultimate goal of the proposal is to develop a low cost rugged portable all optical medical image processing system for breast cancer diagnostics with mammograms. Optical image processing techniques are inherently fast in view of parallel processing. This laboratory is involved during the last ten years in innovating techniques of all optical Fourier and wavelet transforms for image processing. A self adaptive optical Fourier processing system, using photo induced dichroism in a Bacteriorhodopsin film was experimentally demonstrated with applications in noise reduction, edge enhancement and band pass filtering in real time. Application of these powerful techniques for enhancement of medical images is the object of this project. Preliminary results on three mammograms demonstrated the feasibility. By playing with one knob (rotating the analyzer in the optical system) either the micro calcification clusters or the surrounding dense tissue can be selectively displayed. The technique is fast and the scan rate of mammograms is only limited by the frame rate of the CCD camera. An integrated architecture is proposed using electronic optical interfaces. Analog images of mammograms and phantoms will be investigated initially. Both commercially available standard as well as custom designed objects will be used for a thorough contrast detail analysis.
The system will be made versatile so that it can accept medical images in analog as well as digital format. The focus is on optimizing the experimental arrangement and study a large number of mammograms in collaboration with the Radiology group of our medicalzchool in Worcester and carry out relevant statistical analysis. Bacteriorhodopsin films are stable up to 140 degrees C and environmental friendly. As no interference is involved in the experiments, vibration isolation and even a coherent light source are not required. The system designed already with a portable and energy efficient battery operated solid state laser is field deployable. With potential new advances in semiconductor lasers on small chips, it may be possible to further decrease the size and cost resulting in a small handy signal enhancing magnifier. The purpose of the investigation is not to compete with the expensive digital techniques for image processing but to develop a low cost portable instrument accessible to rural areas for quick screening of large number of mammograms.
描述(申请人提供):该提案的最终目标是开发一种低成本、坚固耐用的便携式全光学医学图像处理系统,用于乳腺癌的乳房X光检查诊断。考虑到并行处理,光学图像处理技术本质上是快速的。在过去的十年里,这个实验室致力于图像处理的全光学傅里叶变换和小波变换的创新技术。利用细菌视紫红质薄膜的光致二向色性,建立了一种自适应光学傅立叶处理系统,并在实时降噪、边缘增强和带通滤波等方面得到了应用。应用这些强大的技术来增强医学图像是本项目的目标。三次乳房X光检查的初步结果证明了这种方法的可行性。通过拨动一个旋钮(旋转光学系统中的分析仪),可以选择性地显示微钙化团或周围致密的组织。该技术速度快,并且乳房X光照片的扫描速率仅受CCD摄像机的帧速率的限制。提出了一种使用电光接口的集成体系结构。最初将对乳房X光照片和体模的模拟图像进行调查。商业上可用的标准对象以及定制设计的对象都将用于彻底的对比细节分析。
该系统将变得多功能,这样它就可以接受模拟和数字格式的医学图像。重点是优化实验安排,与我们伍斯特医学院放射科小组合作研究大量乳房X光照片,并进行相关统计分析。细菌视紫红质薄膜的稳定性高达140摄氏度,而且对环境友好。由于实验中不涉及干涉,因此不需要隔振,甚至不需要相干光源。该系统已经设计了便携式和高能效的电池供电的固态激光器,可以在现场部署。随着小型芯片半导体激光器的潜在新进展,有可能进一步减小尺寸和成本,从而产生一种小型方便的信号增强放大器。调查的目的不是与昂贵的数字图像处理技术竞争,而是开发一种低成本的便携式仪器,供农村地区使用,用于快速筛查大量乳房X光照片。
项目成果
期刊论文数量(3)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Spectral phase based medical image processing.
基于光谱相位的医学图像处理。
- DOI:10.1016/j.acra.2004.09.017
- 发表时间:2005
- 期刊:
- 影响因子:4.8
- 作者:Kothapalli,Sri-Rajasekhar;Yelleswarapu,ChandraS;Naraharisetty,SriramG;Wu,Pengfei;Rao,DVGLN
- 通讯作者:Rao,DVGLN
Optical Fourier techniques for medical image processing and phase contrast imaging.
- DOI:10.1016/j.optcom.2007.05.072
- 发表时间:2008-04
- 期刊:
- 影响因子:2.4
- 作者:C. Yelleswarapu;Sri-Rajasekhar Kothapalli;D. Rao
- 通讯作者:C. Yelleswarapu;Sri-Rajasekhar Kothapalli;D. Rao
Nonlinear optical Fourier filtering technique for medical image processing.
用于医学图像处理的非线性光学傅立叶滤波技术。
- DOI:10.1117/1.1953287
- 发表时间:2005
- 期刊:
- 影响因子:3.5
- 作者:Kothapalli,Sri-Rajasekhar;Wu,Pengfei;Yelleswarapu,ChandraS;Rao,DVGLN
- 通讯作者:Rao,DVGLN
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Devulapalli V. Rao其他文献
Devulapalli V. Rao的其他文献
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{{ truncateString('Devulapalli V. Rao', 18)}}的其他基金
Fourier Phase Contrast Microscopy Technique for Biomedical Research
用于生物医学研究的傅里叶相差显微镜技术
- 批准号:
7924651 - 财政年份:2009
- 资助金额:
$ 19.24万 - 项目类别:
Medical Image Processing Using Optical Fourier Technique
使用光学傅里叶技术的医学图像处理
- 批准号:
6542529 - 财政年份:2002
- 资助金额:
$ 19.24万 - 项目类别: