Global Network Data Center

该提案由三角研究所（RTI）和北卡罗来纳大学（UNC）提交，作为NICHD全球妇女和儿童健康研究网络的数据协调中心（DCC）。一个强大的科学家团队，包括提议的PI， T.D. Hartwell博士，和联合PI， dr。RTI的Rao和Poole以及北卡罗来纳大学的教师将领导该项目，并提供整体研究协调，包括研究设计、数据管理、统计分析、材料开发、生物标本收集、通用程序培训、质量控制程序的实施以及孕产妇和儿童健康方面的专业知识。已经召集了一批经验丰富的工作人员，包括统计学家、程序编制员、数据协调员、流行病学家、医学人类学家和国际妇幼保健专家，以支持该网络。所有这些工作人员在协调多中心研究方面都有丰富的经验。我们建议设立一个内部管理委员会来监督网络的DCC操作，该委员会将设立DCC协议小组，与网络调查员就每个协议进行合作。我们建议使用计算机辅助数据收集方法来收集各种网络协议（例如，分布式数据入口）的大部分数据。我们已经在许多多地点研究中使用了这些方法。我们的通讯网络将围绕电子邮件和一个项目网站建立，该网站将尽可能用于传播项目报告和其他信息。我们建议协助研究单位为研究购买计算机设备，在评估程序和干预措施交付方面协调培训每个国家的现场工作人员，协助跟踪、培训和生物标本收集的质量控制，协助协调和分析定性研究的数据，协助材料开发，分析研究数据并协助稿件准备。此外，RTI/UNC将为整个研究提供后勤支持。这包括安排电话会议和会议，在这些会议上做记录，分发学习材料。我们还将在每个国家雇用现场数据收集协调员。

This proposal is submitted by Research Triangle Institute (RTI) and the University of North Carolina (UNC) to serve as the Data Coordinating Center (DCC) for the NICHD Global Network for Women's and Children's Health Research. A strong team of scientists including the proposed PI, Dr. T.D. Hartwell, and Co-PIs, Drs. Rao and Poole of RTI, and faculty from UNC will lead the project and will provide overall study coordination, including study design, data management, statistical analysis, materials development, biological specimen collection, training in common procedures, implementation of quality control procedures, and expertise in maternal and child health. An experienced staff of statisticians, programmers, data coordinators, epidemiologist, medical anthropologists and international and maternal and child health specialists have been assembled to support the Network. All of this staff have a great deal of experience in coordinating multicenter studies. We propose to have an Internal Management Committee oversee the DCC operations for the Network which will set up DCC Protocol Teams to work with Network Investigators on each protocol. We proposed to use computer assisted data collection methods to collect the majority of the data for the various Network protocols (e.g., Distributed Data Entry). We have used these methods in many multisite studies. Our communications network will be built around e-mail and a project web site which will be used to disseminate project reports and other information whenever possible. We propose to assist Research Units in purchasing computer equipment for the study, to coordinate training site staff in each country in assessment procedures and intervention delivery, to assist in tracking, training, and quality control for biological specimen collection, to assist in coordinating and analyzing data for qualitative studies, to assist in materials development, to analyze the study data and to assist in manuscript preparation. In addition, RTI/UNC will provide logistic support for the entire study. This includes setting up conference calls and meetings, taking minutes at these meetings, and distributing study materials. We also will hire on-site data collection coordinators in each country.