Effects of Prenatal malnutrition on socio-emotional development: Evidence from Young Lives

产前营养不良对社会情感发展的影响:来自年轻生命的证据

基本信息

  • 批准号:
    2277502
  • 负责人:
  • 金额:
    --
  • 依托单位:
  • 依托单位国家:
    英国
  • 项目类别:
    Studentship
  • 财政年份:
    2019
  • 资助国家:
    英国
  • 起止时间:
    2019 至 无数据
  • 项目状态:
    已结题

项目摘要

OverviewAn important source of the observed variation in cross-country economic performance are differences in human capital endowment (Mankiw, Romer and Weil, 1992). In particular, health has been shown to be an important determinant of outcomes for developing countries (Bleakley, 2010). There is growing evidence to support the Foetal Origins Hypothesis - that adverse nutritional shocks experienced by the mother during the gestation period have significant impacts on future health/human capital outcomes for the offspring, and hence their future earning potential (Almond, Currie and Duque, 2018). While evidence of the impacts on future physical health outcomes are well established, the impact of on mental wellbeing and the development of socio-emotional abilities remains relatively unexplored.Modelling the development of health capital, using the conceptual framework developed by Heckman (2007) and co-authors, this project will examine the effect of nutritional shocks experienced in utero on an individual's well-being and socio-emotional outcomes later in adolescence in developing countries. For this purpose, data from the Young Lives Survey will be combined with objective regional rainfall and food price data, which indicate exogenous shocks to maternal nutrition. The overall aim of this research is to consider:Does in utero exposure to nutritional shocks have a causal effect on future mental well-being, specifically socio-emotional functioning?Do these effects manifest at a specific stage of development: within childhood, adolescence, or early adulthood?ContextModern contributions in economics addresses criticisms of earlier work in epidemiology, and employ extensive hypothesis testing (Paneth and Susser, 1995). Economists have tested the predictions of the hypothesis on a broad series of outcomes beyond health, including educational attainment and employment prospects (Currie and Hyson, 1999; Oreopoulos et al., 2008), marital status (Vogel, Siow and Brandt, 2010), and inter-generational effects (Currie and Moretti, 2007); subjecting it to rigorous testing.Studies of effects on health are predominantly concerned with physical health, with a few recent exceptions, and only two studies have provided evidence on developing countries. Adhvaryu et al. (2014) assess the effect of cocoa price shocks in Ghana in year of birth on the likelihood of experiencing severe psychological distress, while Adhvaryu et al. (2015) focus on the effect of prenatal exposure to temperature shocks in predicting depressive symptoms from a cross-section of adults in 19 countries. Uniquely, this research will emphasise the effect on socio-emotional abilities such as peer-relations, self-esteem, personality and emotional functions from a nutritional shock experienced in utero. Impact This research expands on existing literature, broadening the scope of outcomes studied to include socio-emotional competencies and -given repeated measurements of data - examines how effects manifest at different stages of development. The findings will carry significance for public health policy decisions: mental health disorders constitute 13 percent of the global disease burden, depression alone representing the third largest single contribution to the global disease burden (Collins et al., 2011). The cost to society is highest for developing countries, both in terms of healthcare costs and the effects on social development, yet these countries are least equipped to offer treatment and support. Given the importance of socio-emotional skills and pro-social behaviour in childhood, adolescence, and subsequently in the labour market (Hay, Payne and Chadwick, 2004), the findings could have radical implications. Simple interventions aimed at improving maternal nutrition could have substantial effect in mitigating costs for developing countries - suggesting the optimum time to intervene to improve an individual's opportunities is before they are even born.
跨国经济表现差异的一个重要来源是人力资本禀赋的差异(Mankiw, Romer和Weil, 1992)。特别是,健康已被证明是发展中国家成果的一个重要决定因素(Bleakley, 2010年)。越来越多的证据支持胎儿起源假说,即母亲在怀孕期间经历的不良营养冲击对后代未来的健康/人力资本结果产生重大影响,从而影响他们未来的收入潜力(Almond, Currie和Duque, 2018)。虽然对未来身体健康结果影响的证据已经确立,但对心理健康和社会情感能力发展的影响仍然相对未被探索。利用Heckman(2007)及其合著者开发的概念框架,对健康资本的发展进行建模,该项目将研究在发展中国家,子宫内经历的营养冲击对个人在青春期后期的福祉和社会情感结果的影响。为此目的,青年生活调查的数据将与客观的区域降雨和粮食价格数据相结合,这些数据表明了对孕产妇营养的外源冲击。这项研究的总体目标是考虑:子宫内暴露于营养冲击是否对未来的心理健康,特别是社会情感功能有因果影响?这些影响是否在特定的发展阶段显现:在童年、青春期或成年早期?背景经济学的现代贡献解决了对流行病学早期工作的批评,并采用了广泛的假设检验(Paneth和Susser, 1995)。经济学家已经在健康之外的一系列广泛的结果上测试了该假设的预测,包括教育程度和就业前景(Currie and Hyson, 1999; Oreopoulos等人,2008),婚姻状况(Vogel, Siow和Brandt, 2010),以及代际影响(Currie和Moretti, 2007);对其进行严格的测试。关于对健康的影响的研究主要涉及身体健康,最近有几个例外,只有两项研究提供了关于发展中国家的证据。Adhvaryu等人(2014)评估了加纳出生年份的可可价格冲击对经历严重心理困扰的可能性的影响,而Adhvaryu等人(2015)则关注了产前暴露于温度冲击对预测19个国家成年人抑郁症状的影响。独特的是,这项研究将强调在子宫内经历的营养休克对社会情感能力的影响,如同伴关系、自尊、个性和情感功能。本研究扩展了现有文献,扩大了研究结果的范围,包括社会情感能力,并在重复测量数据的情况下,研究了影响在不同发展阶段的表现。这些发现将对公共卫生政策决策具有重要意义:精神健康障碍占全球疾病负担的13%,仅抑郁症就占全球疾病负担的第三大单一因素(Collins等人,2011)。就医疗费用和对社会发展的影响而言,发展中国家的社会成本最高,但这些国家最不具备提供治疗和支持的能力。考虑到社会情感技能和亲社会行为在童年、青春期以及随后的劳动力市场中的重要性(Hay, Payne和Chadwick, 2004),这些发现可能会产生根本性的影响。旨在改善产妇营养的简单干预措施可能会对减轻发展中国家的成本产生重大影响——这表明干预以改善个人机会的最佳时机是在他们出生之前。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

其他文献

吉治仁志 他: "トランスジェニックマウスによるTIMP-1の線維化促進機序"最新医学. 55. 1781-1787 (2000)
Hitoshi Yoshiji 等:“转基因小鼠中 TIMP-1 的促纤维化机制”现代医学 55. 1781-1787 (2000)。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
LiDAR Implementations for Autonomous Vehicle Applications
  • DOI:
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
生命分子工学・海洋生命工学研究室
生物分子工程/海洋生物技术实验室
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
吉治仁志 他: "イラスト医学&サイエンスシリーズ血管の分子医学"羊土社(渋谷正史編). 125 (2000)
Hitoshi Yoshiji 等人:“血管医学与科学系列分子医学图解”Yodosha(涉谷正志编辑)125(2000)。
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:
Effect of manidipine hydrochloride,a calcium antagonist,on isoproterenol-induced left ventricular hypertrophy: "Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,K.,Teragaki,M.,Iwao,H.and Yoshikawa,J." Jpn Circ J. 62(1). 47-52 (1998)
钙拮抗剂盐酸马尼地平对异丙肾上腺素引起的左心室肥厚的影响:“Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:

的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('', 18)}}的其他基金

An implantable biosensor microsystem for real-time measurement of circulating biomarkers
用于实时测量循环生物标志物的植入式生物传感器微系统
  • 批准号:
    2901954
  • 财政年份:
    2028
  • 资助金额:
    --
  • 项目类别:
    Studentship
Exploiting the polysaccharide breakdown capacity of the human gut microbiome to develop environmentally sustainable dishwashing solutions
利用人类肠道微生物群的多糖分解能力来开发环境可持续的洗碗解决方案
  • 批准号:
    2896097
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
A Robot that Swims Through Granular Materials
可以在颗粒材料中游动的机器人
  • 批准号:
    2780268
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Likelihood and impact of severe space weather events on the resilience of nuclear power and safeguards monitoring.
严重空间天气事件对核电和保障监督的恢复力的可能性和影响。
  • 批准号:
    2908918
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Proton, alpha and gamma irradiation assisted stress corrosion cracking: understanding the fuel-stainless steel interface
质子、α 和 γ 辐照辅助应力腐蚀开裂:了解燃料-不锈钢界面
  • 批准号:
    2908693
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Field Assisted Sintering of Nuclear Fuel Simulants
核燃料模拟物的现场辅助烧结
  • 批准号:
    2908917
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Assessment of new fatigue capable titanium alloys for aerospace applications
评估用于航空航天应用的新型抗疲劳钛合金
  • 批准号:
    2879438
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Developing a 3D printed skin model using a Dextran - Collagen hydrogel to analyse the cellular and epigenetic effects of interleukin-17 inhibitors in
使用右旋糖酐-胶原蛋白水凝胶开发 3D 打印皮肤模型,以分析白细胞介素 17 抑制剂的细胞和表观遗传效应
  • 批准号:
    2890513
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
CDT year 1 so TBC in Oct 2024
CDT 第 1 年,预计 2024 年 10 月
  • 批准号:
    2879865
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship
Understanding the interplay between the gut microbiome, behavior and urbanisation in wild birds
了解野生鸟类肠道微生物组、行为和城市化之间的相互作用
  • 批准号:
    2876993
  • 财政年份:
    2027
  • 资助金额:
    --
  • 项目类别:
    Studentship

相似海外基金

Prenatal and Early Childhood Biomass Smoke Exposure and Child Neurodevelopment
产前和幼儿期生物质烟雾暴露与儿童神经发育
  • 批准号:
    8618378
  • 财政年份:
    2014
  • 资助金额:
    --
  • 项目类别:
Prenatal and Early Childhood Biomass Smoke Exposure and Child Neurodevelopment
产前和幼儿期生物质烟雾暴露与儿童神经发育
  • 批准号:
    8841357
  • 财政年份:
    2014
  • 资助金额:
    --
  • 项目类别:
Measuring the effects of prenatal alcohol exposure on placenta methylation
测量产前酒精暴露对胎盘甲基化的影响
  • 批准号:
    8739309
  • 财政年份:
    2013
  • 资助金额:
    --
  • 项目类别:
Measuring the effects of prenatal alcohol exposure on placenta methylation
测量产前酒精暴露对胎盘甲基化的影响
  • 批准号:
    8623558
  • 财政年份:
    2013
  • 资助金额:
    --
  • 项目类别:
Prenatal stress biology, infant body composition and obesity risk
产前应激生物学、婴儿身体成分和肥胖风险
  • 批准号:
    8112558
  • 财政年份:
    2010
  • 资助金额:
    --
  • 项目类别:
Elucidating adiposity in a mouse model of prenatal undernutrition
阐明产前营养不良小鼠模型中的肥胖
  • 批准号:
    8133071
  • 财政年份:
    2010
  • 资助金额:
    --
  • 项目类别:
Prenatal stress biology, infant body composition and obesity risk
产前应激生物学、婴儿身体成分和肥胖风险
  • 批准号:
    7949940
  • 财政年份:
    2010
  • 资助金额:
    --
  • 项目类别:
Measuring the impact of prenatal alcohol exposure on the fetal epigenome
测量产前酒精暴露对胎儿表观基因组的影响
  • 批准号:
    8151065
  • 财政年份:
    2010
  • 资助金额:
    --
  • 项目类别:
Elucidating adiposity in a mouse model of prenatal undernutrition
阐明产前营养不良小鼠模型中的肥胖
  • 批准号:
    7872659
  • 财政年份:
    2010
  • 资助金额:
    --
  • 项目类别:
Prenatal stress biology, infant body composition and obesity risk
产前应激生物学、婴儿身体成分和肥胖风险
  • 批准号:
    8700433
  • 财政年份:
    2010
  • 资助金额:
    --
  • 项目类别:
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了