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Infant hearing for modulated tones

婴儿对调制音调的听力

基本信息

批准号：
6613549
负责人：
BARBARA K CONE
金额：
$ 10万
依托单位：
UNIVERSITY OF ARIZONA
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
起止时间：
2003-06-15 至 2007-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/6613549
关键词：
auditory discrimination auditory threshold clinical research electroencephalography electrophysiology hearing disorders human subject infant human (0-1 year) psychophysics sound frequency

项目摘要

DESCRIPTION (provided by applicant): There are theoretical and practical problems to be solved concerning the characterization of hearing sensitivity and sound discrimination abilities in infants. Knowledge of these hearing capabilities is key to determining appropriate habilitation strategies when infants are detected with hearing loss. This project addresses the challenge of characterizing hearing in infants using electrophysiologic responses to amplitude and frequency modulated tones. In conjunction with electrophysiologic methods, age-specific psychophysical measures will be employed to estimate threshold and discrimination abilities in young infants. If we are successful, it may be possible to relate electrophysiologic correlates of hearing sensitivity and central auditory nervous system maturation to perceptual abilities. The long-term goals of this research are to understand how and when infants develop the capacity to detect, discriminate and perceive speech and the evaluation of this development through electrophysiologic and psychophysical methods. The building blocks of speech understanding are defined as 1) hearing sensitivity for "speech frequencies" (500-4000 Hz), 2) temporal processing as reflected in neural phase-locking for modulated tones in the speech frequencies; 3) sensitivity to and discrimination of amplitude modulation and frequency modulation; 4) discrimination of complex sounds composed of two or more modulated components. The research plan is developed to explore these building blocks of speech understanding using auditory electrophysiology and psychophysics to describe the time course and dynamics of responsiveness to amplitude (AM) and frequency (FM) modulated tones and complex sounds composed of multiple carder and modulation frequencies. The research outcomes will contribute new knowledge about how the human auditory system develops the capacity to respond to and discriminate complex signals. This research will also result in methods for assessing threshold sensitivity and sound discrimination in infants that can be applied to those at risk for hearing loss or other auditory dysfunction.

描述（申请人提供）：关于婴儿听力敏感性和声音辨别能力的表征，尚有理论和实践问题需要解决。当婴儿被发现患有听力损失时，了解这些听力能力是确定适当的康复策略的关键。该项目解决了利用对调幅和调频音调的电生理反应来表征婴儿听力特征的挑战。结合电生理学方法，将采用特定年龄的心理物理测量来估计幼儿的阈值和辨别能力。如果我们成功了，就有可能将听力敏感性和中枢听觉神经系统成熟度的电生理相关性与感知能力联系起来。这项研究的长期目标是了解婴儿如何以及何时发展出检测、辨别和感知言语的能力，并通过电生理学和心理物理学方法评估这种发展。语音理解的构建块被定义为 1) “语音频率”(500-4000 Hz) 的听力敏感性，2) 时间处理（反映在语音频率调制音调的神经锁相中）； 3）对调幅和调频的敏感度和辨别力； 4) 辨别由两个或多个调制成分组成的复杂声音。该研究计划旨在利用听觉电生理学和心理物理学来探索语音理解的这些构建模块，以描述对幅度（AM）和频率（FM）调制音调以及由多个卡德和调制频率组成的复杂声音的响应的时间过程和动态。研究成果将贡献关于人类听觉系统如何发展响应和辨别复杂信号的能力的新知识。这项研究还将产生评估婴儿阈值敏感性和声音辨别力的方法，可应用于那些有听力损失或其他听觉功能障碍风险的人。