Regional Deep South Project Export Center (RESPECT)

描述(申请人提供)：阿拉巴马州黑带的非洲裔美国人，位于美国南部腹地，是美国最贫穷的人口之一，慢性病和健康差距带来了不成比例的负担。南方腹地的非洲裔美国公民的死亡率是白人公民的两倍。这源于糖尿病和结直肠癌等显著可治疗疾病的较高发病率、患病率和死亡率。非裔美国人占黑带人口的60%以上，该地区35%的人口生活在美国的贫困水平以下。作为南方腹地的一家领先的研究机构，我们感到有道义上的义务和学术上的资格来解决该地区严重的健康差距。目标。我们建议成立区域深南项目出口中心(REPORT)，其主要目标将是系统地调查种族偏见的病因和生物伦理影响，最终目标是消除糖尿病和结直肠癌方面的健康差距。方法：研究方法。我们将在阿拉巴马大学伯明翰分校S少数民族健康和研究中心的基础上，与阿拉巴马州历史上的黑人学院和大学(HBCU)建立培训联盟，并与指定的少数民族社区组织正式建立其他合作伙伴关系。我们建议1)两个基于感知种族歧视理论的研究项目，将调查糖尿病和结直肠癌护理中的种族偏见；2)调查种族偏见及其消除的试点项目，以成熟的研究基础设施为基础，预先承诺在解决医疗保健差距方面卓越；3)目标人群中具有独特潜力的外展网络，在缩小健康差距方面取得真正进展；4)通过阿拉巴马州HBCU和UAB的合作计划，培养和发展少数族裔科学家和熟练的卫生专业人员，UAB是一所主要的研究型大学，招收了25%的少数族裔学生。尊重目标将通过四个相互关联但不同的单位来实现，这些单位将包括行政、研究(糖尿病和癌症)、培训和外联核心。意义重大。通过学术和社区参与的独特伙伴关系，尊重方案的发展有可能减少少数群体的健康差距。我们还相信，通过未来的临床试验、研究项目和推广计划，它将提高深度南非裔美国人社区成员的自我效能。

DESCRIPTION (provided by applicant): The African-American population in Alabama's Black Belt, in the heart of the Deep South, is one of the nation's poorest and carries a disproportionate burden of chronic diseases and health disparities. African American citizens in the Deep South have mortality rates up to twice that of their white counterparts. This stems from higher incidence, prevalence, and mortality from eminently treatable conditions such as diabetes mellitus and colorectal cancer. African Americans comprise more than 60% of the population of the Black Belt, a region with 35% of its population living below the U.S. poverty level. As a leading research institution in the Deep South, we feel morally obligated and academically qualified to address this region's significant health disparities. Objectives. We propose the formation of the Regional Deep South Project Export Center (RESPECT) of Excellence for Minority Health, the main objective of which will be to systematically investigate the etiologies and bioethical implications of racial bias, with the ultimate goal of eliminating health disparities in diabetes and colorectal cancer. Methods. We will build on the University of Alabama at Birmingham (UAB)'s Minority Health and Research Center by establishing a training consortium with the Historically Black Colleges and Universities (HBCUs) in Alabama and formalizing other partnerships with specified minority community organizations. We propose 1) two research projects, grounded in theory of perceived racial discrimination, that will investigate racial bias in diabetes and colorectal cancer care; 2) pilot projects investigating racial bias and its elimination, anchored on a well-established research infrastructure with a prior commitment to excellence in resolving healthcare disparities; 3) an outreach network within the targeted population with a unique potential to make real progress in reducing health disparities, and 4) a plan for training and developing minority scientists and skilled health professionals through the partnership of Alabama's HBCUs and UAB, a major research university with 25% minority enrollment. The RESPECT objectives will be accomplished through four linked, but distinct units, which will include Administrative, Research (diabetes and cancer), Training, and Outreach Cores. Significance. The development of the RESPECT program has the potential to reduce health disparities in minority populations through a unique partnership of academic and community involvement. We also believe that it will improve the self-efficacy of members of the Deep South African-American community through future clinical trials, research projects, and outreach programs.