Genetic Recombination/Genomic Rearrangements Conference

基因重组/基因组重排会议

• 批准号: 6673102
• 负责人: SUSAN THOMAS LOVETT
• 金额: $ 0.7万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6673102
• 关键词: DNA repair; gene rearrangement; genetic recombination; meeting /conference /symposium; transposon /insertion element

DESCRIPTION (provided by applicant): This application requests partial funding for the 2003 and 2005 FASEB summer research conference on Genetic Recombination and Genomic Rearrangements. The 2003 conference will be held July 26-31 at Snowmass village, Colorado and will be the tenth of a highly successful series of bi-annual conferences on genetic recombination. These conferences join investigators studying many diverse aspects of genetic recombination, in a range of biological systems and with different experimental approaches. Presentations will introduce new and unpublished work on timely questions in the field and will encourage discussion from all participants. Eight plenary sessions will involve topics such as recombination mechanisms, properties of prokaryotic and eukaryotic recombination, meiotic processes, the role of recombinational processes in repair of DNA damage, site-specific recombination and transposition, and genomic rearrangements. Forty speakers, among the best experimentalists and thinkers in these particular areas, have agreed to present their most recent and unpublished work. Several timely issues will be discussed including the role of the breast cancer susceptibility gene BRCA2 in the control of recombination, the role of recombination in repair of the replication fork and the cell cycle checkpoint response to DNA damage and its influence on repair and recombination. Characterization of recombination and repair factors known to underlie human syndromes will propensity to cancer will be discussed, using mammalian and other model genetic systems. Approximately 160 other participants will be chosen from among the applicants to the conference. While maintaining rigorous standards of excellence in selecting participants, every attention will be paid to achieving a balanced representation of age, gender, race and geography. All will be encouraged to participate in discussion, workshops and poster sessions. There will be a workshop on a controversial topic, the role of the Mus81 complexes in recombination intermediate processing, and two poster sessions, each lasting two days, will provide an additional forum for presentation of current work. The 2005 will be organized similarly but will feature different speakers. By emphasizing truly exceptional research in a modestly sized conference setting, the FASEB conference provide unique opportunities for the exchange of information, technology and perspective among new and established investigators in the recombination field.

描述(由申请者提供)：本申请要求为2003年和2005年FASEB关于基因重组和基因组重排的夏季研究会议提供部分资金。2003年会议将于7月26日至31日在科罗拉多州的斯诺马斯村举行，这将是关于基因重组的非常成功的两年一次的系列会议中的第十次。这些会议与研究人员一起研究基因重组的许多不同方面，在一系列生物系统中，并使用不同的实验方法。演讲将介绍关于实地及时问题的新的和未发表的工作，并将鼓励所有参与者进行讨论。八次全体会议将涉及重组机制、原核和真核重组的性质、减数分裂过程、重组过程在DNA损伤修复中的作用、特定部位重组和转座以及基因组重排等主题。40位演讲者，在这些特定领域中最好的实验者和思想家中，已经同意展示他们最新和未发表的作品。讨论的问题包括乳腺癌易感基因BRCA2在重组调控中的作用，重组在复制分叉修复中的作用，细胞周期对DNA损伤的检查点反应及其对修复和重组的影响。利用哺乳动物和其他模型遗传系统，将讨论已知的构成人类综合征基础的重组和修复因子的特征将导致癌症的倾向。将从参加会议的申请者中选出大约160名其他与会者。在保持挑选参与者的严格优秀标准的同时，将尽一切努力实现年龄、性别、种族和地域的均衡代表性。将鼓励所有人参加讨论、研讨会和海报会议。将有一个关于一个有争议的话题的研讨会，即MUS81复合体在重组中间过程中的作用，以及两个海报会议，每次为期两天，将提供一个额外的论坛来展示当前的工作。2005年的组织方式类似，但将有不同的发言者。通过强调在中等规模的会议环境中进行真正特殊的研究，FASEB会议为重组领域的新老研究人员提供了交流信息、技术和观点的独特机会。