Genetic Recombination/Genomic Rearrangements Conference

基因重组/基因组重排会议

• 批准号: 6673102
• 负责人: SUSAN THOMAS LOVETT
• 金额: $ 0.7万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6673102
• 关键词: DNA repair; gene rearrangement; genetic recombination; meeting /conference /symposium; transposon /insertion element

DESCRIPTION (provided by applicant): This application requests partial funding for the 2003 and 2005 FASEB summer research conference on Genetic Recombination and Genomic Rearrangements. The 2003 conference will be held July 26-31 at Snowmass village, Colorado and will be the tenth of a highly successful series of bi-annual conferences on genetic recombination. These conferences join investigators studying many diverse aspects of genetic recombination, in a range of biological systems and with different experimental approaches. Presentations will introduce new and unpublished work on timely questions in the field and will encourage discussion from all participants. Eight plenary sessions will involve topics such as recombination mechanisms, properties of prokaryotic and eukaryotic recombination, meiotic processes, the role of recombinational processes in repair of DNA damage, site-specific recombination and transposition, and genomic rearrangements. Forty speakers, among the best experimentalists and thinkers in these particular areas, have agreed to present their most recent and unpublished work. Several timely issues will be discussed including the role of the breast cancer susceptibility gene BRCA2 in the control of recombination, the role of recombination in repair of the replication fork and the cell cycle checkpoint response to DNA damage and its influence on repair and recombination. Characterization of recombination and repair factors known to underlie human syndromes will propensity to cancer will be discussed, using mammalian and other model genetic systems. Approximately 160 other participants will be chosen from among the applicants to the conference. While maintaining rigorous standards of excellence in selecting participants, every attention will be paid to achieving a balanced representation of age, gender, race and geography. All will be encouraged to participate in discussion, workshops and poster sessions. There will be a workshop on a controversial topic, the role of the Mus81 complexes in recombination intermediate processing, and two poster sessions, each lasting two days, will provide an additional forum for presentation of current work. The 2005 will be organized similarly but will feature different speakers. By emphasizing truly exceptional research in a modestly sized conference setting, the FASEB conference provide unique opportunities for the exchange of information, technology and perspective among new and established investigators in the recombination field.

描述（由申请人提供）：本申请要求为2003年和2005年FASEB遗传修饰和基因组重排夏季研究会议提供部分资金。 2003年的会议将于7月26日至31日在科罗拉多的斯诺马斯村举行，这将是一年两次的遗传重组会议中非常成功的第十次。 这些会议加入研究人员研究基因重组的许多不同方面，在一系列生物系统和不同的实验方法。 专题介绍将介绍关于该领域及时问题的新的和未发表的工作，并鼓励所有与会者进行讨论。 八个全体会议将涉及的主题，如重组机制，原核和真核重组的性质，减数分裂过程，重组过程中的作用，DNA损伤的修复，位点特异性重组和转座，基因组重排。 40位演讲者，在这些特定领域中最好的实验家和思想家，同意展示他们最新的未发表的工作。 几个及时的问题将被讨论，包括乳腺癌易感基因BRCA2在重组控制中的作用，重组在修复复制叉和细胞周期检查点对DNA损伤的反应及其对修复和重组的影响。 利用哺乳动物和其他模型遗传系统，将讨论已知的构成人类综合征基础的重组和修复因子的特征。 大约160名其他与会者将从申请参加会议的人中选出。 在甄选参与者时保持严格的优秀标准，同时将十分注意实现年龄、性别、种族和地域的均衡代表性。 将鼓励所有人参加讨论、讲习班和海报会议。 将有一个有争议的主题，Mus81复合物在重组中间处理中的作用，和两个海报会议，每个持续两天，将提供一个额外的论坛，介绍目前的工作。 2005年的会议将以同样的方式组织，但将有不同的发言者。 通过强调在一个适度规模的会议环境中进行真正卓越的研究，FASEB会议为重组领域的新老研究人员之间交流信息，技术和观点提供了独特的机会。