Mechanisms of Membrane Transport Gordon Conference 2003

膜传输机制戈登会议 2003

• 批准号: 6677730
• 负责人: BLISS FORBUSH
• 金额: $ 1.76万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-06-15 至 2004-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6677730
• 关键词: biological transport; meeting /conference /symposium; membrane proteins; travel

DESCRIPTION (provided by applicant): Funds are requested to help support a Gordon Research Conference, Mechanisms of Membrane Transport, to be held from June 15-20 in 2003 at Holderness School, Plymouth, New Hampshire. This meeting continues a very successful series, held every two years, on topical subjects of high interest to the membrane transport field. This year we will highlight the tremendous advances in understanding that have been enabled by the recent availability of high-resolution structures of membrane channels and transporters. These developments are of great biological significance, and as outlined herein, are both timely and medically relevant. The subjects are important to a wide range of clinical disciplines, and have particular applicability to kidney and gastrointestinal function and neuronal excitability. The meeting will also incorporate advances in the physical basis for membrane protein structure, molecular dynamics modeling of solute movements through channels, and single-molecule approaches to elucidation of mechanism. They will naturally bring together scientists from a wide range of disciplines and promote fruitful interactions that otherwise would probably never occur. Relevant disciplines include biochemistry, biophysics, physiology, cell biology, molecular biology, genetics, pharmacology, and internal medicine. The program is organized to focus on selected transporter families for which crystal structures are available or will soon become available. The meeting includes 31 regular talks and 2 special talks, organized in 9 sessions. The speakers will plan their talks for a very mixed audience, and the attendance of students, fellows, and clinicians will be encouraged. The poster sessions will be strongly promoted, and further emphasized by the selection of four 'short selected talks'. Young investigators will be especially encouraged to attend, present their work, and participate in discussions.

描述（由申请人提供）： 要求提供资金，以帮助支持将于2003年6月15日至20日在新罕布什尔州普利茅斯的Holidays学校举行的戈登研究会议，膜运输机制。这次会议延续了非常成功的系列，每两年举行一次，对膜传输领域高度感兴趣的主题。今年，我们将重点介绍最近获得的膜通道和转运蛋白的高分辨率结构所带来的理解上的巨大进步。这些发展具有重要的生物学意义，如本文所述，既及时又具有医学意义。这些主题对广泛的临床学科都很重要，并且特别适用于肾脏和胃肠道功能以及神经元兴奋性。会议还将包括膜蛋白结构的物理基础，溶质通过通道运动的分子动力学建模，以及阐明机制的单分子方法的进展。它们自然会将来自广泛学科的科学家聚集在一起，促进富有成效的互动，否则可能永远不会发生。相关学科包括生物化学、生物物理学、生理学、细胞生物学、分子生物学、遗传学、药理学和内科学。该计划的组织重点是选定的运输家庭的晶体结构可用或即将成为可用。会议包括31场例行会谈和2场专题会谈，共组织9场。演讲者将计划他们的谈话非常混合的观众，并鼓励学生，研究员和临床医生的出席。海报会议将得到大力推广，并通过选择四个“简短的精选演讲”进一步强调。将特别鼓励年轻的研究人员参加，介绍他们的工作，并参与讨论。