Neurofibromatosis Foundation International Consortium

神经纤维瘤病基金会国际联盟

• 批准号: 6652971
• 负责人: David H Gutmann
• 金额: $ 7万
• 依托单位: CHILDREN'S TUMOR FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-06-01 至 2004-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6652971
• 关键词: meeting /conference /symposium; neurofibromatosis; neurofibromatosis type 1 protein /gene; travel

DESCRIPTION (provided by applicant): Funding is requested to support the next meeting of the National Neurofibromatosis Foundation International Consortium for the Molecular and Cell Biology of NF1 and NF2 to be held June 1-4, 2003 at the Hotel Jerome in Aspen, Colorado. Beginning with the first meeting in 1985, these conferences have served as the catalyst for many of the fundamental discoveries that have contributed major insights into these important diseases of the nervous system. These meetings provide a regular forum to bring together molecular and cell biologists, geneticists, clinicians, and others familiar with NF1 and NF2 to share their latest research findings and experiences. Moreover, these meetings have proven to be exceptional opportunities from scientists and clinical researchers to form new collaborative ventures. NNFF Consortia have been instrumental in the rapid advances in the molecular understanding ofNF 1 and NF2, including the cloning of the responsible genes, establishment of diagnostic tests, exploration of protein functions, development of anima models, and creation of a network of patients and clinicians to facilitate clinical trials. Given the rapid scientific progress and subsequent translation to clinical practice, it is necessary to hold these meetings annually to promote synergy, facilitate collaboration, and enable translational research. The 2003 Consortium meeting has been organized as an open meeting that will be advertised to the general scientific community. Each of six platform sessions will be co-chaired by two experts in the field who will guide discussion of the presented work and its relevance to the overall session topic. These sessions will also include invited speakers from the NF research community and other presentations to be selected from submitted abstracts. Participation by junior investigators will be encouraged and the organizers anticipate, on the basis of previous Consortium meetings, that a substantial percentage of the speakers will be young investigators. Speakers will be instructed to allow time for open discussion among all participants. In addition, loner talks by two keynote speakers who are leaders in scientific fields or emerging technologies that are directly relevant to NF research will be incorporated into the scientific sessions. Two poster sessions will also be held which will allow investigators to present abstracts not selected for one of the oral sessions. In addition to updating investigators working on NF 1 and NF2 on the latest research developments, this meeting will help to identify critical gaps in our knowledge as well as strategies and collaborations to address them. An improved understanding of the molecular basis of NF1 and NF2 will play an essential role in developing improved therapies for the complications of these disorders and has broad implications to the fields of developmental neurobiology and cancer research.

描述（由申请人提供）： 要求资助支持NF1和NF2的分子和细胞生物学国际国家神经瘤病基金会下次会议，2003年6月1日至4日在科罗拉多州阿斯彭的Jerome举行。从1985年的第一次会议开始，这些会议一直是许多基本发现的催化剂，这些发现对神经系统的这些重要疾病有了重大见解。这些会议提供了一个常规的论坛，将分子和细胞生物学家，遗传学家，临床医生以及其他熟悉NF1和NF2的人汇总在一起，以分享他们最新的研究结果和经验。此外，这些会议已被证明是科学家和临床研究人员组建新合作企业的杰出机会。 NNFF联盟对NF 1和NF2的分子理解的快速进步发挥了作用，包括克隆负责的基因，建立诊断测试，探索蛋白质功能，动物模型的发展以及创建患者和临床医生网络，以促进临床试验。鉴于科学进步的快速进步以及随后的临床实践的转化，有必要每年举行这些会议，以促进协同作用，促进协作并实现转化研究。 2003年的财团会议已被组织为公开会议，该会议将为一般科学界做广告。六个平台会议中的每一个都将由该领域的两名专家共同主持，他们将指导讨论提出的工作及其与整个会话主题的相关性。这些会议还将包括来自NF研究社区的受邀演讲者以及将从提交摘要中选择的其他演讲。将鼓励初级调查人员的参与，组织者预计，根据先前的财团会议，很大一部分的演讲者将是年轻的调查员。演讲者将被指示让所有参与者之间的公开讨论时间。此外，两位主题演讲者是科学领域的领导者或与NF研究直接相关的新兴技术的领导者的孤独者会谈。还将举行两次海报会议，这将使调查人员能够提出未在其中一个课程中选择的摘要。除了更新从事NF 1和NF2的研究人员外，这次会议还将有助于确定我们知识的关键差距，以及解决方案的策略和协作。对NF1和NF2的分子基础的改进理解将在开发这些疾病并发症的改善疗法方面起着至关重要的作用，并对发育神经生物学和癌症研究领域具有广泛的影响。