New Perspectives in Transporter Biology-FASEB Conference

转运蛋白生物学新视角-FASEB 会议

• 批准号: 6672461
• 负责人: ROBERT H EDWARDS
• 金额: $ 3.2万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-06-01 至 2004-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6672461
• 关键词: health science research; meeting /conference /symposium; membrane transport proteins; travel

DESCRIPTION (provided by applicant): This application requests support of a conference to be held under the auspices of the Federation of American Societies of Experimental Biology (FASEB) entitled "New Perspectives in Transporter Biology." This is the fourth bi-annual FASEB conference on the subject and is scheduled to be held from July 5 - July 10, 2003 at the Omni Tucson, in Tucson Arizona. Recent developments will make the meeting of great interest to a wide range of investigators, and we expect attendance by approximately 160 scientists. This conference will focus on the role of transport proteins in a number of biological systems, from renal physiology to synaptic transmission. The principles elucidated in one system have already begun to help illuminate the role of membrane transport in others. In addition, the meeting will address the function of transport proteins at multiple levels, from protein structure to behavior of the organism. Biophysical studies at high resolution have indeed already suggested novel roles for various transport proteins not anticipated from classical measurements of radiotracer flux. The meeting will thus provide an unusual opportunity for interaction between many different groups, including physiologists, molecular and cell biologists, biochemists, biophysicists, and structural biologists. The range of biological questions addressed will also encourage interactions between diverse groups. In addition to the role of transporters in normal physiology, the meeting will consider their role in disease (e.g., drug abuse and neural degeneration) and in drug delivery. The conference will consist of nine oral scientific session over five days (morning and evening), and afternoon poster sessions. The topics include epithelial transport, transport in disease, astrocyte-neuron interactions, regulation of transporters by membrane trafficking and changes in intrinsic transport activity, their role in signalling, intracellular transporters, transport mechanism and protein structure. Each oral session will be followed by a panel discussion of the topic. To promote the advancement of junior faculty, the most exciting poster submissions will be selected for short oral presentations during the regular oral sessions.

描述（由申请人提供）：本申请要求支持由美国实验生物学学会联合会（FASEB）主办的题为“转运体生物学的新视角”的会议。这是FASEB关于该主题的第四届两年一次的会议，计划于2003年7月5日至7月10日在亚利桑那州图森市的Omni Tucson举行。最近的发展将使这次会议引起广泛的研究人员的极大兴趣，我们预计将有大约160名科学家出席。本次会议将重点讨论转运蛋白在许多生物系统中的作用，从肾脏生理学到突触传递。在一个系统中阐明的原理已经开始帮助阐明膜运输在其他系统中的作用。此外，会议将讨论转运蛋白在多个层面的功能，从蛋白质结构到生物体的行为。高分辨率的生物物理研究确实已经提出了各种运输蛋白的新作用，这是放射性示踪剂通量的经典测量所没有预料到的。因此，这次会议将为包括生理学家、分子和细胞生物学家、生物化学家、生物物理学家和结构生物学家在内的许多不同群体之间的互动提供一个不同寻常的机会。解决的生物问题范围也将鼓励不同群体之间的互动。除了转运蛋白在正常生理中的作用外，会议还将审议它们在疾病（例如，药物滥用和神经变性）和药物传递中的作用。会议将包括为期五天的九场口头科学会议（上午和晚上），以及下午的海报会议。主题包括上皮运输，疾病中的运输，星形细胞-神经元的相互作用，转运蛋白通过膜运输的调节和内在转运活性的变化，它们在信号传导中的作用，细胞内转运蛋白，转运机制和蛋白质结构。每次口头会议之后将有一个专题小组讨论。为了促进青年教师的进步，我们将在定期的口头会议上选出最令人兴奋的海报作品进行简短的口头报告。