CARDIAC CELL VOLUME REGULATION IN HEALTH AND DISEASE

健康和疾病中的心肌细胞体积调节

• 批准号: 6743716
• 负责人: CLIVE M BAUMGARTEN
• 金额: $ 36.25万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-08-16 至 2007-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6743716
• 关键词: cardiac myocytes; cell morphology; cell osmotic pressure; cellular pathology; fluorescent dye /probe; heart cell; heart metabolism; ion transport; laboratory rabbit; lipid metabolism; membrane permeability; microelectrodes; myocardial ischemia /hypoxia; reperfusion; stretch receptors; video microscopy; voltage /patch clamp

项目成果

Identification of a peptide toxin from Grammostola spatulata spider venom that blocks cation-selective stretch-activated channels.

• DOI: 10.1085/jgp.115.5.583
• 发表时间: 2000-05
• 期刊: The Journal of general physiology
• 作者: Suchyna TM;Johnson JH;Hamer K;Leykam JF;Gage DA;Clemo HF;Baumgarten CM;Sachs F
• 通讯作者: Sachs F

Atrial natriuretic factor: implications for cardiac pacing and electrophysiology.

心房钠尿因子：对心脏起搏和电生理学的影响。

• DOI: 10.1111/j.1540-8159.1994.tb01353.x
• 发表时间: 1994
• 期刊: Pacing and clinical electrophysiology : PACE
• 作者: Clemo,HF;Baumgarten,CM;Stambler,BS;Wood,MA;Ellenbogen,KA
• 通讯作者: Ellenbogen,KA

Osmotic gradient-induced water permeation across the sarcolemma of rabbit ventricular myocytes.

• DOI: 10.1085/jgp.107.4.503
• 发表时间: 1996-04
• 期刊: The Journal of general physiology
• 作者: Suleymanian MA;Baumgarten CM
• 通讯作者: Baumgarten CM

EGFR kinase regulates volume-sensitive chloride current elicited by integrin stretch via PI-3K and NADPH oxidase in ventricular myocytes.

EGFR激酶可调节整合素通过PI-3K伸展而引起的体积敏感的氯化物电流，在心室心肌细胞中通过PI-3K和NADPH氧化酶。

• DOI: 10.1085/jgp.200509366
• 发表时间: 2006-03
• 期刊: JOURNAL OF GENERAL PHYSIOLOGY
• 影响因子: 3.8
• 作者: Browe, David M;Baumgarten, Clive M
• 通讯作者: Baumgarten, Clive M

Modulation of rabbit ventricular cell volume and Na+/K+/2Cl- cotransport by cGMP and atrial natriuretic factor.

CGMP和心房NATRIATERETIC因子的兔心室体积和Na+/K+/2CL-共转移的调节。

• DOI: 10.1085/jgp.100.1.89
• 发表时间: 1992-07
• 期刊: JOURNAL OF GENERAL PHYSIOLOGY
• 影响因子: 3.8
• 作者: Clemo, H F;Feher, J J;Baumgarten, C M
• 通讯作者: Baumgarten, C M