Development of a Skin Cancer Quality of Life Insturment

皮肤癌生活质量测试仪的开发

• 批准号: 6794321
• 负责人: JOHN S RHEE
• 金额: $ 6.8万
• 依托单位: MEDICAL COLLEGE OF WISCONSIN
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-05-01 至 2006-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794321
• 关键词: behavioral /social science research tag; clinical research; data collection methodology /evaluation; face; head; human subject; interview; neck; psychological adaptation; psychometrics; quality of life; questionnaires; skin neoplasms; therapy adverse effect

DESCRIPTION (provided by applicant): Malignancies of the skin are the most common cancers among humans. Non-melanoma skin cancers (NMSC), which include basal cell carcinoma and squamous cell carcinoma, have reached epidemic proportions in the United States and are now a major public health concern. The cervicofacial region is most affected by cutaneous malignancies, with approximately 80 percent of NMSC occurring in the head and neck. Treatment of cervicofacial skin cancers also is more likely to result in significant patient morbidity, because of the functional and cosmetic importance of this region. Adverse consequences may include physical, functional deficits, as well as, psychosocial issues related to potential disfigurement. Unlike other malignancies, skin cancer has not been well investigated in terms of patient quality of life (QOL) assessment. Furthermore, no validated disease-specific QOL instrument currently exists for skin cancer. Our proposed study seeks to fill this gap by creating and beginning the initial validation of a disease-specific instrument to measure QOL issues relevant for NMSC patients and initiating the process of determining the QOL of patients with NMSC using the newly developed scale.

描述(由申请人提供)： 皮肤恶性肿瘤是人类最常见的癌症。非黑色素瘤皮肤癌(NMSC)，包括基底细胞癌和鳞状细胞癌，在美国已经达到流行的比例，现在是一个主要的公共卫生问题。颈部面部受皮肤恶性肿瘤的影响最大，大约80%的NMSC发生在头部和颈部。 颈部面部皮肤癌的治疗也更有可能导致显著的患者发病率，因为这一区域在功能和美容方面的重要性。不良后果可能包括身体、功能缺陷，以及与潜在毁容相关的心理社会问题。与其他恶性肿瘤不同，皮肤癌在患者生活质量(QOL)评估方面尚未得到很好的研究。此外，目前还没有经过验证的皮肤癌疾病特异性生活质量测量工具。 我们建议的研究试图通过创建和开始疾病特异性工具的初步验证来填补这一空白，以测量与NMSC患者相关的生活质量问题，并启动使用新开发的量表来确定NMSC患者的生活质量的过程。